Profilin-2 is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Interactions PFN2 has been shown to interact with ROCK1, Vasodilator-stimulated phosphoprotein, CFAP263 and FMNL1.
References
Further reading
External links Overview of all the structural information available in the PDB for UniProt: P35080 (Human Profilin-2) at the PDBe-KB. Overview of all the structural information available in the PDB for UniProt: Q9JJV2 (Mouse Profilin-2) at the PDBe-KB.






