Thymus-specific serine protease is an enzyme that in humans is encoded by the PRSS16 gene. This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.
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Further reading
External links PRSS16 human gene location in the UCSC Genome Browser. PRSS16 human gene details in the UCSC Genome Browser.






