chemistry

Peter J. Myler

Peter J. Myler is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Peter J. Myler rather than just read about it. In short: Peter John Myler is a biochemist, medical researcher and educator. He is professor, principal investigator, and supervisor at the Center for Global Infectious Disease Research in Seattle, Washington.

Key takeaways

Peter J. Myler belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Peter J. Myler to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Peter J. Myler from memory before moving on to harder problems.

Reference excerpt

Peter John Myler is a biochemist, medical researcher and educator. He is professor, principal investigator, and supervisor at the Center for Global Infectious Disease Research in Seattle, Washington.

Education Myler earned both his Bachelor of Science degree and his PhD in biochemistry (in 1982), at the University of Queensland in Australia.

Career In 1993, Myler became an assistant professor in pathobiology at the University of Washington. At the University of Washington's Department of Global Health, he is an affiliate professor, both with Global Health and with Biomedical Informatics and Medical Education. His research focuses on genome-scale technologies (next-generation sequencing, mRNA profiling and proteomics), bioinformatics and molecular approaches to study gene function and protein structure in infectious disease organisms. His laboratory works to discover novel drug and vaccine strategies against global infectious diseases. Some of his research integrated aspects of molecular biology with epidemiological and clinical concerns, including species of the pathogens Trypanosoma and Leishmania.

Selected publications Myler, Peter J.; Fasel, Nicolas J., eds. (2008). Leishmania: After the Genome. Caister Academic Press Limited. ISBN 978-1-904455-28-8. El-Sayed, Najib M.; Myler, Peter J.; Bartholomeu, Daniella C.; Nilsson, Daniel (2005-07-15). "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease". Science. 309 (5733): 409–15. Bibcode:2005Sci...309..409E. doi:10.1126/science.1112631. hdl:11336/80500. PMID 16020725. Ivens, Alasdair C.; Peacock, Christopher S.; Worthey, Elizabeth A.; Murphy, Lee; et al. (2005-07-15). "The genome of the kinetoplastid parasite, Leishmania major". Science. 309 (5733): 436–42. Bibcode:2005Sci...309..436I. doi:10.1126/science.1112680. PMC 1470643. PMID 16020728. Aslett, Martin; Aurrecoechea, Cristina; Berriman, Matthew; Brestelli, John; et al. (January 2010). "TriTrypDB: a functional genomic resource for the Trypanosomatidae". Nucleic Acids Research. 38 (Database issue): D457–62. doi:10.1093/nar/gkp851. PMC 2808979. PMID 19843604. El-Sayed, Najib M.; Myler, Peter J.; Blandin, Gaëlle; Berriman, Matthew (2005-07-15). "Comparative genomics of trypanosomatid parasitic protozoa". Science. 309 (5733): 404–409. Bibcode:2005Sci...309..404E. doi:10.1126/science.1112181. PMID 16020724. Yamada, Shinya; Hatta, Masato; Staker, Bart L.; Watanabe, Shinji; et al. (2010-08-05). "Biological and structural characterization of a host-adapting amino acid in influenza virus". PLOS Pathogens. 6 (8) e1001034. doi:10.1371/journal.ppat.1001034. PMC 2916879. PMID 20700447. Martínez-Calvillo, Santiago; Yan, Shaofeng; Nguyen, Dan; Fox, Mark; et al. (May 2003). "Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region". Molecular Cell. 11 (5): 1291–1299. doi:10.1016/s1097-2765(03)00143-6. PMID 12769852. Myler, Peter J.; Audleman, Lindsey; deVos, Theo; Hixson, Greg (1999-03-16). "Leishmania major Friedlin Chromosome 1 Has an Unusual Distribution of Protein-Coding Genes". Proceedings of the National Academy of Sciences of the United States of America. 96 (6): 2902–2906. Bibcode:1999PNAS...96.2902M. doi:10.1073/pnas.96.6.2902. PMC 15867. PMID 10077609. Stuart, Kenneth D.; Weeks, Reitha; Guilbride, Lys; Myler, Peter J. (1992-09-15). "Molecular organization of Leishmania RNA virus 1". Proceedings of the National Academy of Sciences of the United States of America. 89 (18): 8596–8600. Bibcode:1992PNAS...89.8596S. doi:10.1073/pnas.89.18.8596. PMC 49967. PMID 1382295. Martínez-Calvillo, Santiago; Nguyen, Dan; Stuart, Kenneth; Myler, Peter J. (April 2004). "Transcription Initiation and Termination on Leishmania major Chromosome 3". Eukaryotic Cell. 3 (2): 506–517. doi:10.1128/EC.3.2.506-517.2004. PMC 387636. PMID 15075279.

Honors and awards Myler received the BBVA Foundation Frontiers of Knowledge Award for Development Cooperation, 2016.

References

Worked examples

Example 1 — a first encounter with Peter J. Myler

Start with the simplest possible case. Write down what Peter J. Myler claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Peter J. Myler before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Peter J. Myler ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Peter J. Myler

In research: Peter J. Myler appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Peter J. Myler in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Peter J. Myler is common in secondary-school and first-year university syllabi. It links to neighbouring topics American biochemists, Australian biochemists, Biochemists, so understanding it makes those chapters shorter.
In everyday life: Look for Peter J. Myler outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Peter J. Myler in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Peter J. Myler means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Peter J. Myler out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Peter J. Myler in simple terms?

Peter John Myler is a biochemist, medical researcher and educator. He is professor, principal investigator, and supervisor at the Center for Global Infectious Disease Research in Seattle, Washington.

Why does Peter J. Myler matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Peter J. Myler?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Peter J. Myler.