The enzyme phenylpyruvate decarboxylase (EC 4.1.1.43) catalyzes the chemical reaction
phenylpyruvate ⇌ {\displaystyle \rightleftharpoons } phenylacetaldehyde + CO2 This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming). This enzyme is also called phenylpyruvate carboxy-lyase. This enzyme participates in phenylalanine and tryptophan metabolism.
Structural studies As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB: 2NXW.
References
Asakawa T, Wada H, Yamano T (1968). "Enzymatic conversion of phenylpyruvate to phenylacetate". Biochim. Biophys. Acta. 170 (2): 375–91. doi:10.1016/0304-4165(68)90017-2. PMID 4303395.
