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Phi29 holin family

Phi29 holin family is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Phi29 holin family rather than just read about it. In short: The Bacillus subtilis φ29 Holin (φ29 Holin) Family (TC# 1.E.10) is a group of transporters belonging to the Holin Superfamily IV. A representative list of members belonging to the φ29 holin family can be found in the Transporter Classification Database.

Key takeaways

  • Phi29 holin family belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Phi29 holin family to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Phi29 holin family from memory before moving on to harder problems.

Reference excerpt

The Bacillus subtilis φ29 Holin (φ29 Holin) Family (TC# 1.E.10) is a group of transporters belonging to the Holin Superfamily IV. A representative list of members belonging to the φ29 holin family can be found in the Transporter Classification Database. The phage φ29 gene 14 encodes the protein GP14 (TC# 1.E.10.1.1) which is required for phage φ29-promoted host cell lysis. When expressed in E. coli, it leads to cell death without lysis. When expressed together with phage φ29 lysozyme or an unrelated murein-degrading enzyme, cell lysis is also observed. Thus, GP14 is a nonspecific holin in the cytoplasmic membrane of B. subtilis. It is identical to the phage PZA lysis protein and nearly identical to the phage B103 lysis protein. It is 34% identical to the phage GA-1 holin.

See also Holin Lysin Transporter Classification Database

References

As of this edit, this article uses content from "1.E.10 The Bacillus subtilis φ29 Holin (φ29 Holin) Family", which is licensed in a way that permits reuse under the Creative Commons Attribution-ShareAlike 3.0 Unported License, but not under the GFDL. All relevant terms must be followed.

Worked examples

Example 1 — a first encounter with Phi29 holin family

Start with the simplest possible case. Write down what Phi29 holin family claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Phi29 holin family before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Phi29 holin family ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Phi29 holin family

In research
Phi29 holin family appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Phi29 holin family in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Phi29 holin family is common in secondary-school and first-year university syllabi. It links to neighbouring topics Holins, Membrane protein stubs, Protein families, so understanding it makes those chapters shorter.
In everyday life
Look for Phi29 holin family outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Phi29 holin family in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Phi29 holin family means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Phi29 holin family out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Phi29 holin family in simple terms?

The Bacillus subtilis φ29 Holin (φ29 Holin) Family (TC# 1.E.10) is a group of transporters belonging to the Holin Superfamily IV. A representative list of members belonging to the φ29 holin family can be found in the Transporter Classification Database.

Why does Phi29 holin family matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Phi29 holin family?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Phi29 holin family.

Tags

  • Holins
  • Membrane protein stubs
  • Protein families

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