In enzymology, a phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase (EC 2.7.8.20) is an enzyme that catalyzes the chemical reaction
phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose ⇌ {\displaystyle \rightleftharpoons } 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose Thus, the two substrates of this enzyme are phosphatidylglycerol and membrane-derived-oligosaccharide D-glucose, whereas its two products are 1,2-diacyl-sn-glycerol and membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups transferases for other substituted phosphate groups. The systematic name of this enzyme class is phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase. Other names in common use include phosphoglycerol transferase, oligosaccharide glycerophosphotransferase, and phosphoglycerol transferase I. This enzyme participates in glycerolipid metabolism.
References
Jackson BJ, Kennedy EP (1983). "The biosynthesis of membrane-derived oligosaccharides. A membrane-bound phosphoglycerol transferase". J. Biol. Chem. 258 (4): 2394–8. doi:10.1016/S0021-9258(18)32937-5. PMID 6296144.
