In enzymology, phycocyanobilin:ferredoxin oxidoreductase (PcyA, EC 1.3.7.5) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are biliverdin and reduced ferredoxin. Its products are (2R,3Z)-phycocyanobilin and oxidized ferredoxin. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is (3Z)-phycocyanobilin:ferredoxin oxidoreductase. This enzyme participates in the catabolism of heme.
Structural studies As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB: 2D1E, PDB: 2DKE, and PDB: 2G18.
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