Progesterone monooxygenase (EC 1.14.99.4) is an enzyme that catalyzes a chemical reaction that converts the steroid hormone, progesterone, to testosterone acetate. This is part of the mechanism that microorganisms such as Cylindrocarpon radicicola use to break down progesterone
This enzyme is an oxidoreductase, that uses molecular oxygen together with an unknown electron acceptor. The systematic name of this enzyme class is progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating). This enzyme is also called progesterone hydroxylase.
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