Progressive cardiac conduction defect (PCCD) is a hereditary cardiac condition marked by a progressive delay in impulse conduction via the His-Purkinje system, resulting in right or left bundle branch block (RBBB or LBBB), syncope, and occasionally sudden cardiac death.
Cause
Diagnosis When progressive conduction abnormalities in people under 50 with structurally normal hearts are present but skeletal myopathies are absent, progressive cardiac conduction defect is primarily diagnosed, particularly if there is a family history of PCCD.
Treatment At the moment, implanting an implantable pacemaker is the only proven treatment for PCCD, regardless of the underlying cause.
References
Further reading Asatryan, Babken; Medeiros-Domingo, Argelia (April 26, 2019). "Molecular and genetic insights into progressive cardiac conduction disease". EP Europace. 21 (8). Oxford University Press (OUP): 1145–1158. doi:10.1093/europace/euz109. ISSN 1099-5129. PMID 31087102.
External links