Propargylamine is an organic compound with the formula HC≡CCH2NH2. It is a colorless, odorless liquid that is used as a precursor to other compounds. Propargyl amines are produced by reactions of amines with propargyl halides. The behavior of propargyl amine is illustrated by its acylation benzoyl chloride to the amide. A Sonogashira coupling of the terminal alkyne end with another equivalent of benzoylchloride gives the dicarbonyl, a precursor to an oxazole.
Drugs Propargylamine is used in the synthesis of:
Etintidine [69539-53-3] 2-PAT HDAC1/MAO-B-IN-1 [2759855-37-1]
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