Propentofylline (HWA 285) is a xanthine derivative drug with purported neuroprotective effects.
Pharmacology It is a phosphodiesterase inhibitor, and also acts as an adenosine reuptake inhibitor.
Uses Propentofylline was studied as a possible treatment for Alzheimer's disease and multi-infarct dementia, and has been studied, to a lesser extent, as a possible adjunct in the treatment of ischemic stroke, due to its vasodilating properties. Propentofylline is in use as a veterinary medicine in older dogs.
See also Pentoxifylline
External links Methylxanthines (summary of research, including possible multipartite mechanisms)
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