engineering

Propionyl-CoA C2-trimethyltridecanoyltransferase

Propionyl-CoA C2-trimethyltridecanoyltransferase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Propionyl-CoA C2-trimethyltridecanoyltransferase rather than just read about it. In short: In enzymology, a propionyl-CoA C2-trimethyltridecanoyltransferase (EC 2.3.1.154) is an enzyme that catalyzes the chemical reaction 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA ⇌ {\displaystyle \rightleftharpoons } 3-oxopristanoyl-CoA + CoA Thus, the two substrates of this enzyme are 4,8,12-trimethyltridecanoyl-CoA and propanoyl-CoA, whereas its two products are 3-oxopristanoyl-CoA and CoA. This enzyme belongs to…

Key takeaways

Propionyl-CoA C2-trimethyltridecanoyltransferase belongs to engineering; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Propionyl-CoA C2-trimethyltridecanoyltransferase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Propionyl-CoA C2-trimethyltridecanoyltransferase from memory before moving on to harder problems.

Reference excerpt

In enzymology, a propionyl-CoA C2-trimethyltridecanoyltransferase (EC 2.3.1.154) is an enzyme that catalyzes the chemical reaction

4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA ⇌ {\displaystyle \rightleftharpoons } 3-oxopristanoyl-CoA + CoA Thus, the two substrates of this enzyme are 4,8,12-trimethyltridecanoyl-CoA and propanoyl-CoA, whereas its two products are 3-oxopristanoyl-CoA and CoA. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is 4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase. Other names in common use include 3-oxopristanoyl-CoA hydrolase, 3-oxopristanoyl-CoA thiolase, peroxisome sterol carrier protein thiolase, sterol carrier protein, oxopristanoyl-CoA thiolase, peroxisomal 3-oxoacyl coenzyme A thiolase, SCPx, 4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA, and 2-C-4,8,12-trimethyltridecanoyltransferase.

References

Seedorf U, Brysch P, Engel T, Schrage K, Assmann G (1994). "Sterol carrier protein X is peroxisomal 3-oxoacyl coenzyme A thiolase with intrinsic sterol carrier and lipid transfer activity". J. Biol. Chem. 269 (33): 21277–83. doi:10.1016/S0021-9258(17)31960-9. PMID 8063752. Wanders RJ, Denis S, Wouters F, Wirtz KW, Seedorf U (1997). "Sterol carrier protein X (SCPx) is a peroxisomal branched-chain beta-ketothiolase specifically reacting with 3-oxo-pristanoyl-CoA: a new, unique role for SCPx in branched-chain fatty acid metabolism in peroxisomes" (PDF). Biochem. Biophys. Res. Commun. 236 (3): 565–569. Bibcode:1997BBRC..236..565W. doi:10.1006/bbrc.1997.7007. PMID 9245689.

Worked examples

Example 1 — a first encounter with Propionyl-CoA C2-trimethyltridecanoyltransferase

Start with the simplest possible case. Write down what Propionyl-CoA C2-trimethyltridecanoyltransferase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Propionyl-CoA C2-trimethyltridecanoyltransferase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Propionyl-CoA C2-trimethyltridecanoyltransferase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Propionyl-CoA C2-trimethyltridecanoyltransferase

In research: Propionyl-CoA C2-trimethyltridecanoyltransferase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Propionyl-CoA C2-trimethyltridecanoyltransferase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Propionyl-CoA C2-trimethyltridecanoyltransferase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 2.3.1, EC 2.3 stubs, Enzymes of unknown structure, so understanding it makes those chapters shorter.
In everyday life: Look for Propionyl-CoA C2-trimethyltridecanoyltransferase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Propionyl-CoA C2-trimethyltridecanoyltransferase in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Propionyl-CoA C2-trimethyltridecanoyltransferase means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Propionyl-CoA C2-trimethyltridecanoyltransferase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Propionyl-CoA C2-trimethyltridecanoyltransferase in simple terms?

In enzymology, a propionyl-CoA C2-trimethyltridecanoyltransferase (EC 2.3.1.154) is an enzyme that catalyzes the chemical reaction 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA ⇌ {\displaystyle \rightleftharpoons } 3-oxopristanoyl-CoA + CoA Thus, the two substrates of this enzyme are 4,8,12-trime…

Why does Propionyl-CoA C2-trimethyltridecanoyltransferase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Propionyl-CoA C2-trimethyltridecanoyltransferase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Propionyl-CoA C2-trimethyltridecanoyltransferase.