biology

Protein-glucosylgalactosylhydroxylysine glucosidase

Protein-glucosylgalactosylhydroxylysine glucosidase is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Protein-glucosylgalactosylhydroxylysine glucosidase rather than just read about it. In short: The enzyme protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) catalyzes the following chemical reaction: [collagen]-(5R)-5-O-[α-D-glucosyl-(1→2)-β-D-galactosyl]-5-hydroxy-L-lysine + H2O = D-glucose + [collagen]-(5R)-5-O-(β-D-galactosyl)-5-hydroxy-L-lysine It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is protein…

Key takeaways

Protein-glucosylgalactosylhydroxylysine glucosidase belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Protein-glucosylgalactosylhydroxylysine glucosidase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Protein-glucosylgalactosylhydroxylysine glucosidase from memory before moving on to harder problems.

Reference excerpt

The enzyme protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) catalyzes the following chemical reaction:

[collagen]-(5R)-5-O-[α-D-glucosyl-(1→2)-β-D-galactosyl]-5-hydroxy-L-lysine + H2O = D-glucose + [collagen]-(5R)-5-O-(β-D-galactosyl)-5-hydroxy-L-lysine It belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is protein-α-D-glucosyl-1,2-β-D-galactosyl-L-hydroxylysine glucohydrolase. Other names in common use include 2-O-α-D-glucopyranosyl-5-O-α-D-galactopyranosylhydroxy-L-lysine glucohydrolase, and lysine glucohydrolase.

References

Hamazaki H, Hotta K (1979). "Purification and characterization of an α-glucosidase specific for hydroxylysine-linked disaccharide of collagen". J. Biol. Chem. 254 (19): 9682–7. doi:10.1016/S0021-9258(19)83570-6. PMID 385589. Hamazaki H, Hotta K (1980). "Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-α-D-glucopyranosyl-O-β-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens". Eur. J. Biochem. 111 (2): 587–91. doi:10.1111/j.1432-1033.1980.tb04975.x. PMID 7460918. Sternberg M, Spiro RG (1979). "Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney α-glucosidase of high specificity". J. Biol. Chem. 254 (20): 10329–36. doi:10.1016/S0021-9258(19)86713-3. PMID 385599.

Worked examples

Example 1 — a first encounter with Protein-glucosylgalactosylhydroxylysine glucosidase

Start with the simplest possible case. Write down what Protein-glucosylgalactosylhydroxylysine glucosidase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Protein-glucosylgalactosylhydroxylysine glucosidase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Protein-glucosylgalactosylhydroxylysine glucosidase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Protein-glucosylgalactosylhydroxylysine glucosidase

In research: Protein-glucosylgalactosylhydroxylysine glucosidase appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Protein-glucosylgalactosylhydroxylysine glucosidase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Protein-glucosylgalactosylhydroxylysine glucosidase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 3.2.1, EC 3.2 stubs, Enzymes of unknown structure, so understanding it makes those chapters shorter.
In everyday life: Look for Protein-glucosylgalactosylhydroxylysine glucosidase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Protein-glucosylgalactosylhydroxylysine glucosidase in 20 minutes

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Close the page and write down what Protein-glucosylgalactosylhydroxylysine glucosidase means in your own words.
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Work through the three examples above with pen and paper.
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Frequently asked questions

What is Protein-glucosylgalactosylhydroxylysine glucosidase in simple terms?

The enzyme protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) catalyzes the following chemical reaction: [collagen]-(5R)-5-O-[α-D-glucosyl-(1→2)-β-D-galactosyl]-5-hydroxy-L-lysine + H2O = D-glucose + [collagen]-(5R)-5-O-(β-D-galactosyl)-5-hydroxy-L-lysine It belongs to the family of…

Why does Protein-glucosylgalactosylhydroxylysine glucosidase matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Protein-glucosylgalactosylhydroxylysine glucosidase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Protein-glucosylgalactosylhydroxylysine glucosidase.