Protein wntless homolog, commonly known as Wntless, is encoded in humans by the WLS gene. Wntless is a receptor for Wnt proteins in Wnt-secreting cells. Wntless was shown to be a cargo for the retromer complex. It has been found essential for hair follicle induction. A homozygous missense mutation in the WLS gene was identified in Zaki syndrome.
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See also GPR177+receptor,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.






