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Protein xylosyltransferase

Protein xylosyltransferase is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Protein xylosyltransferase rather than just read about it. In short: In enzymology, a protein xylosyltransferase (EC 2.4.2.26) is an enzyme that catalyzes the chemical reaction in which a beta-D-xylosyl residue is transferred from UDP-D-xylose to the sidechain oxygen atom of a serine residue in a protein. This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases.

Key takeaways

  • Protein xylosyltransferase belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Protein xylosyltransferase to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Protein xylosyltransferase from memory before moving on to harder problems.

Reference excerpt

In enzymology, a protein xylosyltransferase (EC 2.4.2.26) is an enzyme that catalyzes the chemical reaction in which a beta-D-xylosyl residue is transferred from UDP-D-xylose to the sidechain oxygen atom of a serine residue in a protein. This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-D-xylose:protein beta-D-xylosyltransferase. Other names in common use include UDP-D-xylose:core protein beta-D-xylosyltransferase, UDP-D-xylose:core protein xylosyltransferase, UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase, UDP-xylose-core protein beta-D-xylosyltransferase, uridine diphosphoxylose-core protein beta-xylosyltransferase, and uridine diphosphoxylose-protein xylosyltransferase. This enzyme participates in the biosynthesis of chondroitin sulfate and glycan structures.

Human proteins XYLT1 XYLT2

See also Xylosyltransferase

References

Stoolmiller AC, Horwitz AL, Dorfman A (1972). "Biosynthesis of the chondroitin sulfate proteoglycan. Purification and properties of xylosyltransferase". J. Biol. Chem. 247 (11): 3525–32. doi:10.1016/S0021-9258(19)45172-7. PMID 5030630. Gotting C, Kuhn J, Zahn R, Brinkmann T, Kleesiek K (2000). "Molecular cloning and expression of human UDP-d-Xylose:proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II". J. Mol. Biol. 304 (4): 517–28. doi:10.1006/jmbi.2000.4261. PMID 11099377.

Worked examples

Example 1 — a first encounter with Protein xylosyltransferase

Start with the simplest possible case. Write down what Protein xylosyltransferase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Protein xylosyltransferase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Protein xylosyltransferase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Protein xylosyltransferase

In research
Protein xylosyltransferase appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Protein xylosyltransferase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Protein xylosyltransferase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 2.4.2, EC 2.4 stubs, Enzymes of unknown structure, so understanding it makes those chapters shorter.
In everyday life
Look for Protein xylosyltransferase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Protein xylosyltransferase in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Protein xylosyltransferase means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Protein xylosyltransferase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Protein xylosyltransferase in simple terms?

In enzymology, a protein xylosyltransferase (EC 2.4.2.26) is an enzyme that catalyzes the chemical reaction in which a beta-D-xylosyl residue is transferred from UDP-D-xylose to the sidechain oxygen atom of a serine residue in a protein. This enzyme belongs to the family of glycosyltransferases, sp…

Why does Protein xylosyltransferase matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Protein xylosyltransferase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Protein xylosyltransferase.

Tags

  • EC 2.4.2
  • EC 2.4 stubs
  • Enzymes of unknown structure

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