The Q-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties. They are poorly understood, but like R-type calcium channels, they appear to be present in cerebellar granule cells. They have a high threshold of activation and relatively slow kinetics. Mutations in the CACNA1A gene that encodes this protein are responsible for familial hemiplegic migraine type 1 (FHM1), episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6).
References
External links Q-Type+Calcium+Channel at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
