Queen bee acid (10-hydroxy-2-decenoic acid or 10-HDA) is a fatty acid found in royal jelly. Queen bee acid is being investigated for its potential pharmacological activities. It promotes neurogenesis of neural stem/progenitor cells (cells capable of differentiating into neurons, astrocytes, or oligodendrocytes) in vitro. In addition, queen bee acid has been reported to have in vitro anti-tumor, anti-biotic, immunomodulatory, estrogenic, neurogenic, and innate immune response modulating activities. In the United States, the Food and Drug Administration has taken legal action against companies that have used unfounded claims of health benefits to market royal jelly products.
See also 10-Hydroxydecanoic acid 2-Decenedioic acid
References
External links Royal Jelly Uses, Side Effects & Warnings, medically reviewed by Drugs.com on Sep 29, 2020. Written by Cerner Multum. Izuta, H.; Chikaraishi, Y.; Shimazawa, M.; Mishima, S.; Hara, H. (2007). "10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-induced Angiogenesis in Human Umbilical Vein Endothelial Cells". Evidence-Based Complementary and Alternative Medicine. 6 (4): 489–494. doi:10.1093/ecam/nem152. PMC 2781774. PMID 18955252.

