biology

Richard Smeyne

Richard Smeyne is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Richard Smeyne rather than just read about it. In short: Richard Jay Smeyne is a neuroscientist who is currently Professor and Chair of the Department of Neuroscience at Thomas Jefferson University, where he is also Director of the Jefferson Comprehensive Parkinson's Disease and Movement Disorder Center at the Vickie and Jack Farber Institute for Neuroscience. His research is focused on the cell biology of Parkinson's disease, as well as neuroprotection.

Key takeaways

Richard Smeyne belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Richard Smeyne to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Richard Smeyne from memory before moving on to harder problems.

Reference excerpt

Richard Jay Smeyne is a neuroscientist who is currently Professor and Chair of the Department of Neuroscience at Thomas Jefferson University, where he is also Director of the Jefferson Comprehensive Parkinson's Disease and Movement Disorder Center at the Vickie and Jack Farber Institute for Neuroscience. His research is focused on the cell biology of Parkinson's disease, as well as neuroprotection. He received his doctorate in neuroanatomy from Thomas Jefferson University in 1989, and undertook postdoctoral training at the Roche Institute of Molecular Biology studying with Dr. Jim Morgan and Tom Curran. As a postdoctoral fellow, Dr. Smeyne, along with colleagues in the Morgan and Curran lab were one of the first to generate a transgenic mouse that expressed the transgene under the control of its cognate promoter. In 1992, following his postdoctoral work, he started his own lab at the Bristol Myers Squibb Pharmaceutical Research Center in Princeton NJ. At BMS, he collaborated with the lab of Dr. Mariano Barbacid to generate and analyze mice carrying mutations of the neurotrophin receptors TrkA, TrkB and TrkC. In 1994, Dr. Smeyne left BMS and was named the Head of the Neurogenetics Program in the Division of CNS Research at Hoffmann-La Roche. In 1996 following the closure of the Roche Institute of Molecular Biology, Dr. Smeyne was recruited to the faculty at Saint Jude Children's Research Hospital, where he joined, as an Associate Member rising to Full Member, in the Department of Developmental Neurobiology. It was at SJCRH that Dr. Smeyne started his research program examining the cellular and molecular underpinnings of Parkinson's disease. In 2016, after 20 years at SJCRH, Dr. Smeyne was recruited to Thomas Jefferson University as a Full Professor and to be Head of the Comprehensive Parkinson's Disease Center. Under his leadership, the JCPDC was named a Center of Excellence by the Parkinson's Foundation. Dr. Smeyne has had a long-standing interest in the cell biology of Parkinson’s disease, with studies examining both environmental and genetic causation. His lab was one the first to show, in animal models of PD, that exercise could modify disease progression, and more recently has been examining the underlying molecular programs responsible for this neuroprotection . He is also recognized for his work examining interactions of the peripheral immune system with that of the brain’s innate immune system immune as well as the role of viruses in the etiology of Parkinson’s disease. Dr. Smeyne has a long history of service to the community. He has previously served as the Chair of the Clinical and Scientific Advisory Board for the Parkinson’s Foundation. as well as continued service on numerous review panels for the NIH, MJFF foundation and Parkinson's' UK. His lab is currently funded by the NIH, Aligning Science Across Parkinson's (Team Tansey) and the Vickie and Jack Farber Foundation for Neuroscience. According to PubMed, Dr. Smeyne has published 125 papers and has an H-Index of 70. He was recently named by research.com to the list of top 1,000 neuroscientists in the USA.

References

External links

Richard Smeyne publications indexed by Google Scholar

Worked examples

Example 1 — a first encounter with Richard Smeyne

Start with the simplest possible case. Write down what Richard Smeyne claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Richard Smeyne before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Richard Smeyne ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Richard Smeyne

In research: Richard Smeyne appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Richard Smeyne in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Richard Smeyne is common in secondary-school and first-year university syllabi. It links to neighbouring topics American scientist stubs, Living people, Neuroscientist stubs, so understanding it makes those chapters shorter.
In everyday life: Look for Richard Smeyne outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Richard Smeyne in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Richard Smeyne means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Richard Smeyne out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Richard Smeyne in simple terms?

Why does Richard Smeyne matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Richard Smeyne?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Richard Smeyne.