A ring forming reaction or ring-closing reaction in organic chemistry is an umbrella term for a variety of reactions that introduce one or more rings into a molecule. A heterocycle forming reaction is a reaction that introduces a new heterocycle. Important classes of ring forming reactions include annulations and cycloadditions. Heterocyclic compounds are useful in spectroscopic identification of compounds, purity criteria, and investigating the molecular electronic structures.
Named ring forming reactions Named ring forming reactions include (not exhaustive):
Azide-alkyne Huisgen cycloaddition Bischler–Napieralski reaction Bucherer carbazole synthesis Danheiser annulation Dieckmann condensation Diels–Alder reaction Feist–Benary synthesis Fiesselmann thiophene synthesis Fischer indole synthesis Gewald reaction Hantzsch pyridine synthesis Larock indole synthesis Paal–Knorr synthesis Pictet–Spengler reaction Pomeranz–Fritsch reaction Ring-closing metathesis Robinson annulation Skraup reaction
See also Ring-closing reactions in Cyclic compound
References
Further reading Michael B. Smith & Jerry March, 2007, "March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure," 6th Ed., New York, NY, USA:Wiley & Sons, ISBN 0470084944, see [1], accessed 19 June 2015. László Kürti & Barbara Czakó, 2005, "Strategic Applications of Named Reactions in Organic Synthesis: Background and Detailed Mechanisms, Amsterdam, NH, NLD:Elsevier Academic Press, 2005ISBN 0124297854, see [2], accessed 19 June 2015.