In genetics, rs5569 (A1287G or G1287A) is a genetic variant. It is a single nucleotide polymorphism (SNP) in the SLC6A2 gene in exon 9. This gene codes the norepinephrine transporter. The SNP is a silent substitution and the nucleotides of both variants code a threonine amino acid. Several research studies have examined the effect of the variant in relation to alcohol dependence, attention deficit hyperactivity disorder, diabetes, major depressive disorder, panic disorder, Tourette syndrome and personality traits. None of the studies have found an association.
References
Further reading E. G. Jonsson, M. M. Nothen, J. P. Gustavsson, H. Neidt, R. Bunzel, P. Propping & G. C. Sedvall (June 1998). "Polymorphisms in the dopamine, serotonin, and norepinephrine transporter genes and their relationships to monoamine metabolite concentrations in CSF of healthy volunteers". Psychiatry Research. 79 (1): 1–9. doi:10.1016/S0165-1781(98)00027-4. PMID 9676821. S2CID 40355623.{{cite journal}}: CS1 maint: multiple names: authors list (link) GeneCards
