biology

S. Ganesh

S. Ganesh is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand S. Ganesh rather than just read about it. In short: Subramaniam Ganesh (born 23 May 1968) is an Indian geneticist, molecular biologist and a professor at the department of biological sciences and bio-engineering of the Indian Institute of Technology, Kanpur. Known for his pioneering studies on Lafora progressive myoclonic epilepsy and other neurodegenerative disorders, Ganesh is an elected fellow of the Indian Academy of Sciences and the National Academy of Sciences…

Key takeaways

S. Ganesh belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect S. Ganesh to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of S. Ganesh from memory before moving on to harder problems.

Reference excerpt

Subramaniam Ganesh (born 23 May 1968) is an Indian geneticist, molecular biologist and a professor at the department of biological sciences and bio-engineering of the Indian Institute of Technology, Kanpur. Known for his pioneering studies on Lafora progressive myoclonic epilepsy and other neurodegenerative disorders, Ganesh is an elected fellow of the Indian Academy of Sciences and the National Academy of Sciences, India. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences in 2008.

Biography

Born on 23 May 1968 in the south Indian state of Tamil Nadu, Ganesh completed his undergraduate studies at the University of Madras in 1988 and earned an MSc in 1990. Subsequently, he joined the Banaras Hindu University for his doctoral studies to secure a PhD in 1996. His post-doctoral work was at the Indian Institute of Science from 1997 to 1998 after which he moved to Japan to start his career as a staff scientist at the RIKEN Brain Science Institute. On his return to India in 2002, he joined the Indian Institute of Technology, Kanpur (IITK) as a member of faculty at the department of biological sciences and bio-engineering (BSBE) where he serves as the P.K. Kelkar Chair Professor. At IITK, he has set up his laboratory of human molecular genetics, popularly known as Ganesh Laboratory, and is the principal investigator, while hosting many research scholars. Ganesh resides in IIT Campus in Kanpur, Uttar Pradesh.

Legacy

Ganesh's research focus has been in the fields of human molecular genetics and neuroscience and he is known to have carried out extensive work on the genetic forms of neurodegenerative disorders. During his early days at IITK, he led a team of scientists researching on the Lafora disease (LD) to establish the role played by LD proteins in protein quality control and their work widened the understanding of the disorder. Later, he focused his work to other neurodegenerative disorders such as central nervous system diseases, cardiovascular disorders and developmental disorders, with emphasis on their pathways, while working on developing new therapeutic protocols. His studies have been documented by way of a number of articles and ResearchGate, an online repository of scientific articles has listed 93 of them. Ganesh is the chief editor of IITK Directions, a Springer publication and has also prepared video lecture courses for the National Programming on Technology Enhanced Learning (NPTEL). The invited speeches delivered by him include the one on the Role of non-coding RNAs in cellular stress response, delivered in 2016 at the 82nd annual meeting of the Indian Academy of Sciences. He serves as an associate editor of the Journal of Genetics of the Indian Academy of Sciences and is a former editorial board member of Meta Gene and Gene Reports, both Elsevier publications.

Awards and honors The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2008. and he received the Scopus Young Indian Scientists Award the same year. He received one more award in 2008, the B. M. Birla Science Prize of the B. M. Birla Science Foundation. The Science Research Council of the Department of Atomic Energy selected him for the Outstanding Research Investigator Award in 2010 and he received the Rajib Goyal Prize of Kurukshetra University in 2011. The National Academy of Sciences, India elected him as a fellow in 2012; the same year as he received the CDRI Award of the Central Drug Research Institute. He received the Basanti Devi Amir Chand Prize of the Indian Council of Medical Research in 2014 and the Scientist Award of the Organisation of Pharmaceutical Producers of India in 2016. He also received the elected fellowship of the Indian Academy of Sciences in 2016. The award orations delivered by him include the 2015 edition of the K. T. Shetty Memorial Oration of the Indian Academy of Neurosciences and he has held research fellowships such as the Alexander von Humboldt fellowship, the Ramanna Fellowship of the Department of Science and Technology, and the Tata Innovation Fellowship of the Department of Biotechnology. In 2012, he featured in the list of Top 25 Scientists in India published by India Today.

Selected bibliography Rai, Anupama; Mishra, Rohit; Ganesh, Subramaniam (15 December 2017). "Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in a mouse model for Lafora disease". Human Molecular Genetics. 26 (24): 4778–4785. doi:10.1093/hmg/ddx357. ISSN 0964-6906. PMID 28973665. Parihar, Rashmi; Ganesh, Subramaniam (1 September 2016). "Autism genes: the continuum that connects us all". Journal of Genetics. 95 (3): 481–483. doi:10.1007/s12041-016-0688-0. ISSN 0022-1333. PMID 27659318. S2CID 4018645. Upadhyay, Mamta; Bhadauriya, Pratibha; Ganesh, Subramaniam (2016). "Heat shock modulates the subcellular localization, stability, and activity of HIPK2". Biochemical and Biophysical Research Communications. 472 (4): 580–584. doi:10.1016/j.bbrc.2016.03.035. PMID 26972256.

Illustrations

Worked examples

Example 1 — a first encounter with S. Ganesh

Start with the simplest possible case. Write down what S. Ganesh claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to S. Ganesh before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about S. Ganesh ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of S. Ganesh

In research: S. Ganesh appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses S. Ganesh in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: S. Ganesh is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1968 births, Academic staff of IIT Kanpur, Banaras Hindu University alumni, so understanding it makes those chapters shorter.
In everyday life: Look for S. Ganesh outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study S. Ganesh in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what S. Ganesh means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain S. Ganesh out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is S. Ganesh in simple terms?

Why does S. Ganesh matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study S. Ganesh?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on S. Ganesh.