SCHEMBL5334361 is a drug which acts as an agonist at the 5-HT2 family of serotonin receptors, and was developed for the treatment of glaucoma. It is a benzazepine derivative structurally related to the anorectic drug lorcaserin. It is selective for 5-HT2A, with an EC50 of 0.4nM at 5-HT2A vs 3.9nM at 5-HT2C and a much lower affinity of 417nM at 5-HT2B.
See also Substituted 3-benzazepine 3C-BZ 4-PhPr-3,5-DMA AL-34662 GSK-189254 IHCH-7113 O-4310 WAY-470 Zalsupindole
References


