SKF-82,958 is a synthetic compound of the 3-benzazepine family that acts as a dopamine D1 and D5 receptor full agonist. SKF-82,958 and similar D1-like-selective full agonists like SKF-81,297 and 6-Br-APB produce characteristic anorectic effects, hyperactivity and self-administration in animals, with a similar but not identical profile to that of dopaminergic stimulants such as amphetamine. SKF-82,958 was also subsequently found to act as an agonist of ERα with negligible activity at ERβ, making it a subtype-selective estrogen.
See also Substituted 3-benzazepine Cyclized phenethylamine
References
External links SKF-82958 - Isomer Design


