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chemistry

SKF-89976A

SKF-89976A is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand SKF-89976A rather than just read about it. In short: SKF-89976A is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1. Synthesis Ex 1: Finkelstein Sn2 alkylation between 1,1-Diphenyl-4-bromobutene [6078-95-1] (1) & Ethyl nipecotate [5006-62-2] (2) gives [89203-62-3] (3).

SKF-89976A — main illustration
SKF-89976A — illustration

Key takeaways

  • SKF-89976A belongs to chemistry; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect SKF-89976A to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of SKF-89976A from memory before moving on to harder problems.

Reference excerpt

SKF-89976A is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1.

Synthesis

Ex 1: Finkelstein Sn2 alkylation between 1,1-Diphenyl-4-bromobutene [6078-95-1] (1) & Ethyl nipecotate [5006-62-2] (2) gives [89203-62-3] (3). Optional saponification of the ester group gives the title amino-acid compound (4).

Related compounds

References

External links Borden, L. A.; Murali Dhar, T. G.; Smith, K. E.; Weinshank, R. L.; Branchek, T. A.; Gluchowski, C. (1994). "Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1". European Journal of Pharmacology. 269 (2): 219–224. doi:10.1016/0922-4106(94)90089-2. PMID 7851497.

Illustrations

SKF-89976A illustration
SKF-89976A: Synthesis:[2][3] Patent:[4][5]
Synthesis:[2][3] Patent:[4][5]
SKF-89976A: NNC-47-0011:[6] Patent:[7]
NNC-47-0011:[6] Patent:[7]

Worked examples

Example 1 — a first encounter with SKF-89976A

Start with the simplest possible case. Write down what SKF-89976A claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to SKF-89976A before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about SKF-89976A ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of SKF-89976A

In research
SKF-89976A appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses SKF-89976A in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
SKF-89976A is common in secondary-school and first-year university syllabi. It links to neighbouring topics Anticonvulsant stubs, Anticonvulsants, Carboxylic acids, so understanding it makes those chapters shorter.
In everyday life
Look for SKF-89976A outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study SKF-89976A in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what SKF-89976A means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain SKF-89976A out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is SKF-89976A in simple terms?

SKF-89976A is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1. Synthesis Ex 1: Finkelstein Sn2 alkylation between 1,1-Diphenyl-4-bromobutene [6078-95-1] (1) & Ethyl nipecotate [5006-62-2] (2) gives [89203-62-3] (3).

Why does SKF-89976A matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study SKF-89976A?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on SKF-89976A.

Tags

  • Anticonvulsant stubs
  • Anticonvulsants
  • Carboxylic acids
  • GABA reuptake inhibitors
  • Piperidines

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