chemistry

SU-11739

SU-11739 is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand SU-11739 rather than just read about it. In short: SU-11739 (other developmental code names AGN-1133, J-508; also known as N-methyl-N-propargyl-1-aminoindane) is an experimental monoamine oxidase inhibitor (MAOI) that was never marketed. It is a dual or non-selective irreversible monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B) inhibitor, with preference for inhibition of MAO-B over MAO-A.

Key takeaways

SU-11739 belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect SU-11739 to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of SU-11739 from memory before moving on to harder problems.

Reference excerpt

SU-11739 (other developmental code names AGN-1133, J-508; also known as N-methyl-N-propargyl-1-aminoindane) is an experimental monoamine oxidase inhibitor (MAOI) that was never marketed. It is a dual or non-selective irreversible monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B) inhibitor, with preference for inhibition of MAO-B over MAO-A. It is less selective for MAO-B inhibition than AGN-1135 (racemic rasagiline) or rasagiline. In addition to its MAOI activity, SU-11739 has been reported to have strong activity as a catecholamine releasing agent. Similarly to rasagiline, but unlike selegiline and desmethylselegiline, SU-11739 is not a monoaminergic activity enhancer (MAE). The drug is the racemic N-methylated analogue of rasagiline. It is also a ring-cyclized analogue of pargyline with about 20 times the MAOI potency of pargyline. SU-11739 was discovered before rasagiline and was patented in 1965.

References

Illustrations

Worked examples

Example 1 — a first encounter with SU-11739

Start with the simplest possible case. Write down what SU-11739 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to SU-11739 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about SU-11739 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of SU-11739

In research: SU-11739 appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses SU-11739 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: SU-11739 is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1-Aminoindanes, Abandoned drugs, Monoamine oxidase inhibitors, so understanding it makes those chapters shorter.
In everyday life: Look for SU-11739 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study SU-11739 in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what SU-11739 means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain SU-11739 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is SU-11739 in simple terms?

Why does SU-11739 matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study SU-11739?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on SU-11739.