biology

Sagar Sengupta

Sagar Sengupta is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Sagar Sengupta rather than just read about it. In short: Sagar Sengupta is an Indian cancer biologist, a scientist at the National Institute of Immunology, India and Director, National Institute of Biomedical Genomics, Kalyani, India. Known for his studies on genome integrity, tumor suppressor gene and oncogenes, Sengupta is an elected fellow of all the three major Indian science academies namely the National Academy of Sciences, India, the Indian National Science Academy…

Key takeaways

Sagar Sengupta belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Sagar Sengupta to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Sagar Sengupta from memory before moving on to harder problems.

Reference excerpt

Sagar Sengupta is an Indian cancer biologist, a scientist at the National Institute of Immunology, India and Director, National Institute of Biomedical Genomics, Kalyani, India. Known for his studies on genome integrity, tumor suppressor gene and oncogenes, Sengupta is an elected fellow of all the three major Indian science academies namely the National Academy of Sciences, India, the Indian National Science Academy and the Indian Academy of Sciences. He has been a Jagadish Chandra Bose (JC Bose) Fellow since 2018. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2011.

Biography

Sagar Sengupta was born in the Indian state of West Bengal, earned a postgraduate degree from the University of Calcutta and secured a PhD from the Indian Institute of Science. He did his post doctoral studies at the Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC) in Strasbourg, France and completed it at the National Cancer Institute of the National Institutes of Health. Subsequently, he joined the National Institute of Immunology, India in 2004 as a faculty. He served in National Institute of Immunology till 2022 as a Grade VII Staff Scientist. In November 2022, Sengupta became the Director of National Institute of Biomedical Genomics, Kalyani, West Bengal on deputation from National Institute of Immunology. From November 2023, he hasalso been Director (Additional Charge) of National Brain Research Centre, Manesar, Haryana. The permanent residence of Sengupta is in Gurgaon, Haryana.

Professional profile Sengupta's research focus is on the changes in the signaling pathways during cancer development and he has carried out studies on the tumour suppressor genes and oncogenes. During his post-doctoral days at the National Institutes of Health (NIH), he undertook a project on NIH grant to study the Determination of regulatory mechanisms for BLM helicase. His studies have been documented by way of a number of articles and ResearchGate, an online repository of scientific articles has listed over 50 of them. The complete list of his publications can be found at: https://www.ncbi.nlm.nih.gov/myncbi/1t7wpVLc8yt/bibliography/public/ He has also undertaken several projects on behalf of the government agencies such as the Department of Science and Technology, the Science and Engineering Research Board, the Department of Biotechnology and the Council of Scientific and Industrial Research and the Board of Research in Nuclear Sciences as the principal investigator and is associated with the Department of Biotechnology as a member of its Task force on Cancer Biology, the expert committee on Promotion and Popularization of Biotechnology and the Expert Committee for Twinning RD program for North Eastern Region.

Awards and honors Sengupta received the Best Thesis Award for his doctoral thesis from the Indian Institute of Science in 1997. The Department of Biotechnology (DBT) of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2011. The National Academy of Sciences, India elected him as a fellow in 2012 and he became an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy in 2017. He is also a member of the Guha Research Conference. He has been a Jagadish Chandra Bose (JC Bose) Fellow since 2018.

Selected bibliography

Articles Sengupta, Sagar; Harris, Curtis C. (2005). "p53: traffic cop at the crossroads of DNA repair and recombination". Nature Reviews Molecular Cell Biology. 6 (1): 44–55. doi:10.1038/nrm1546. ISSN 1471-0080. PMID 15688066. S2CID 11972657. Sengupta, Sagar; Robles, Ana I.; Linke, Steven P.; Sinogeeva, Natasha I.; Zhang, Ran; Pedeux, Remy; Ward, Irene M.; Celeste, Arkady; Nussenzweig, André (13 September 2004). "Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest". J Cell Biol. 166 (6): 801–813. doi:10.1083/jcb.200405128. ISSN 0021-9525. PMC 2172115. PMID 15364958. Sengupta, Sagar; Wasylyk, Bohdan (15 September 2001). "Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2". Genes & Development. 15 (18): 2367–2380. doi:10.1101/gad.202201. ISSN 0890-9369. PMC 312780. PMID 11562347.

Worked examples

Example 1 — a first encounter with Sagar Sengupta

Start with the simplest possible case. Write down what Sagar Sengupta claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Sagar Sengupta before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Sagar Sengupta ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Sagar Sengupta

In research: Sagar Sengupta appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Sagar Sengupta in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Sagar Sengupta is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1968 births, 20th-century Indian biologists, Cancer researchers, so understanding it makes those chapters shorter.
In everyday life: Look for Sagar Sengupta outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Sagar Sengupta in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Sagar Sengupta means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Sagar Sengupta out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Sagar Sengupta in simple terms?

Why does Sagar Sengupta matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Sagar Sengupta?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Sagar Sengupta.