Sarsasapogenin 3β-glucosyltransferase (EC 2.4.1.193) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are sarsasapogenin and UDP-glucose. Its products are asparagoside A (sarsasapogenin 3-O-β-D-glucoside) and uridine diphosphate (UDP). The enzyme was first isolated from the root of the common asparagus (Asparagus officinalis). It is specific for substrate sterols with the uncommon 5β-configuration (sarsasapogenin and smilagenin), that is with a cis-linkage between the A and B rings of the steroid nucleus. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:(3β,5β,25S)-spirostan-3-ol 3-O-β-D-glucosyltransferase. This enzyme is also called uridine diphosphoglucose-sarsasapogenin glucosyltransferase.
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