Single-pixel imaging is a computational imaging technique for producing spatially-resolved images using a single detector instead of an array of detectors (as in conventional camera sensors). A device that implements such an imaging scheme is called a single-pixel camera. Combined with compressed sensing, the single-pixel camera can recover images from fewer measurements than the number of reconstructed pixels. Single-pixel imaging differs from raster scanning in that multiple parts of the scene are imaged at the same time, in a wide-field fashion, by using a sequence of mask patterns either in the illumination or in the detection stage. A spatial light modulator (such as a digital micromirror device) is often used for this purpose. Single-pixel cameras were developed to be simpler, smaller, and cheaper alternatives to conventional, silicon-based digital cameras, with the ability to also image a broader spectral range. Since then, they have been adapted and demonstrated to be suitable for numerous applications in microscopy, tomography, holography, ultrafast imaging, FLIM and remote sensing.
History The origins of single-pixel imaging can be traced back to the development of dual photography and compressed sensing in the mid-2000s. Seminal papers by Takhar et al. and Duarte et al. at Rice University concretised the foundations of the single-pixel imaging technique. It also presented a detailed comparison of different scanning and imaging modalities in existence at that time. These developments were also one of the earliest applications of the digital micromirror device (DMD), developed by Texas Instruments for their DLP projection technology, for structured light detection. Soon, the technique was extended to computational ghost imaging, terahertz imaging, and 3D imaging. Systems based on structured detection were often termed single-pixel cameras, whereas those based on structured illumination were often referred to as computational ghost imaging. By using pulsed-lasers as the light source, single-pixel imaging was applied for time-of-flight measurements used in depth-mapping LiDAR applications. Apart from the DMD, different light modulation schemes were also experimented with liquid crystals and LED arrays. In the early 2010s, single-pixel imaging was exploited in fluorescence microscopy, for imaging biological samples. Coupled with the technique of time-correlated single photon counting (TCSPC), the use of single-pixel imaging for compressive fluorescence lifetime imaging microscopy (FLIM) has also been explored. Since the late 2010s, machine learning techniques, especially Deep learning, have been increasingly used to optimise the illumination, detection, or reconstruction strategies of single-pixel imaging.
Principles
Theory
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![Single-pixel imaging: Schematic of a single-pixel camera using a DMD. The transmitted light (white) from the sample (blue) is modulated by the DMD and collected by a single-pixel detector.[1]](https://upload.wikimedia.org/wikipedia/commons/thumb/6/6a/Single-pixel_imaging.png/500px-Single-pixel_imaging.png?utm_source=en.wikipedia.org&utm_campaign=parser&utm_content=thumbnail)

