Siouxsie Wiles (born Susanna Wiles) is a British microbiologist. Her specialist areas are infectious diseases and bioluminescence. She is based in New Zealand. She is the head of University of Auckland's Bioluminescent Superbugs Lab.
Early life Wiles was born in the United Kingdom and grew up in the UK and South Africa. Her mother is a retired social worker and her father is a business owner.
Education
Ebola was the microbe that started Wiles' interest in microbiology when she was a teenager. During her TEDxChristchurch talk in 2015 she said:
"This is the microbe that got me hooked on microbiology in the first place, because it's both amazing and utterly terrifying. I was a teenager when I first read about Ebola and all I could think of was: How does this turn the human body into a virus producing factory?" The book The Hot Zone by Richard Preston, which focuses on Ebola, was what made Wiles focus her education on medical microbiology. Wiles studied at the University of Edinburgh and graduated in 1997 with a BSc(Hons) in medical microbiology. While an undergraduate, she received a Nuffield Scholarship and worked in the university's School of Biological Sciences. Wiles received her PhD from Edinburgh Napier University, conducting research at the Centre for Ecology and Hydrology (previously known as the Institute of Virology and Environmental Microbiology), which is located in Oxford. During her PhD Wiles first used bioluminescence to create biosensors to monitor the health of environmentally beneficial microbes.
Professional life After completing her PhD, Wiles moved to Imperial College London for a post-doctoral research position on tuberculosis. In 2007 she became a lecturer at Imperial College's Department of Infectious Diseases and Immunity, and in 2009 was awarded a Sir Charles Hercus Fellowship from the Health Research Council of New Zealand and moved to the University of Auckland. Wiles is the head of the university's Bioluminescent Superbugs Lab. In 2013 she won the Prime Minister's Prize for Science Media Communication which includes prize money of NZ$100,000. Wiles started the company Brightenz that sells kits with which one can create bioluminescent art at home. In 2018 Wiles became science ambassador for House of Science, a not-for-profit venture for raising science literacy in local communities. She was also reelected as general Councillor of the Royal Society Te Apārangi in 2018. Two years later she was on the list of the BBC's 100 Women announced on 23 November 2020. Wiles is also working on finding new antibiotics by screening 10,000 New Zealand fungi for possible medical use.
Bioluminescent Superbugs Lab
Wiles leads the Bioluminescent Superbugs Lab at the University of Auckland which focuses on how glowing bacteria can advance the understanding of microbial infections such as food poisoning, tuberculosis and hospital superbugs. The bioluminescence is used to speed up the process of developing new antibiotics utilising the light emitted from the bacteria, because only living bacteria emit light. About her work Wiles says "My career has been built on making nasty bacteria bioluminescent and using them for all sorts of things, including finding new medicines". New Zealand has some of the highest rates of infectious diseases among developed countries. Globally 700,000 people die each year from drug-resistant diseases.
Science communication
Wiles is passionate about demystifying science for the general public. She is an active blogger on Sciblogs.co.nz, an online podcaster, a commentator on Radio New Zealand and appears on TV shows to discuss science stories in the news. She was one of the eight scientists who fronted the "Great New Zealand Science Project", the New Zealand government's public engagement programme leading to the National Science Challenges in 2012. She commissioned, co-wrote, and appeared with her daughter in the TVNZ online children's science show Siouxsie & Eve Investigate. From 2010 until 2016 Wiles was co-host of the Completely Unnecessary Skeptical Podcast which focused on skepticism in New Zealand. She has also used art and film to communicate scientific ideas: in 2011 she collaborated with Australian graphic artist Luke Harris to produce a series of animated films featuring bioluminescent creatures and their uses in science. The animations on NASA's use of fireflies for the search of extraterrestrial life was selected for inclusion in the 6th Imagine Science Film Festival in New York in 2013, and the Goethe Institute's 2014 Science Film Festival. Wiles collaborated with artist Rebecca Klee on an installation at the Auckland Art in the Dark Festival in 2013, which featured Hawaiian bobtail squid and Aliivibrio fischeri. Wiles thinks that relevant science education should start in primary school, for increasing science literacy and interest in the field more generally.
Her 2015 science communication projects include the Biolumination II exhibition. Wiles is active in the skeptical movement having received the Skeptic of the Year Award from the New Zealand Skeptics in 2016 and attended several NZ Skeptic Conferences. She has also spoken out against anti-vaxxers and other public health related issues. In 2018, Wiles was named as a finalist for New Zealander of the Year Awards for her work on antibiotic-resistant superbugs and infectious diseases. She won the award in 2021 for her leadership in the public communication of New Zealand's COVID-19 response.
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