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Solangepras

Solangepras

Solangepras (INNTooltip International Nonproprietary Name; developmental code name CVN-424), or solengepras (USANTooltip United States Adopted Name), is an inverse agonist of the orphan G protein-coupled receptor 6 (GPR6) which is under development for the treatment of Parkinson's disease. It is a small molecule and is taken by mouth. Solangepras produces hyperlocomotion and reverses haloperidol-induced catalepsy in rodents. It is being developed by Cerevance. As of October 2024, solangepras is in phase 3 clinical trials.

See also List of investigational Parkinson's disease drugs

References

External links Solengepras (CVN424) - Cerevance

Tags

  • 2,4-Difluorophenyl compounds
  • Experimental drugs
  • Inverse agonists
  • Nervous system drug stubs
  • Piperidines
  • Pyridopyrazines
  • Secondary amines
  • Tetrahydrofurans