chemistry

Solute carrier organic anion transporter family member 1B3

Solute carrier organic anion transporter family member 1B3 is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Solute carrier organic anion transporter family member 1B3 rather than just read about it. In short: Solute carrier organic anion transporter family member 1B3 (SLCO1B3) also known as organic anion-transporting polypeptide 1B3 (OATP1B3) is a protein that in humans is encoded by the SLCO1B3 gene. OATP1B3 is a 12-transmembrane domain influx transporter.

Key takeaways

Solute carrier organic anion transporter family member 1B3 belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Solute carrier organic anion transporter family member 1B3 to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Solute carrier organic anion transporter family member 1B3 from memory before moving on to harder problems.

Reference excerpt

Solute carrier organic anion transporter family member 1B3 (SLCO1B3) also known as organic anion-transporting polypeptide 1B3 (OATP1B3) is a protein that in humans is encoded by the SLCO1B3 gene. OATP1B3 is a 12-transmembrane domain influx transporter. Normally expressed in the liver, the transporter functions to uptake large, non-polar drugs and hormones from the portal vein.

Clinical significance OATP1B3 has also been identified as a transporter aberrantly expressed in prostate cancer and implicated in prostate cancer progression. Increasing mRNA expression of OATP1B3 was also correlated to prostate cancer Gleason score. In addition, lower expression of OATP1B3 mRNA was also detected in testicular cancer.

Substrates Small molecules that are transported by SLCO1B3 include:

Illustrations

Worked examples

Example 1 — a first encounter with Solute carrier organic anion transporter family member 1B3

Start with the simplest possible case. Write down what Solute carrier organic anion transporter family member 1B3 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Solute carrier organic anion transporter family member 1B3 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Solute carrier organic anion transporter family member 1B3 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Solute carrier organic anion transporter family member 1B3

In research: Solute carrier organic anion transporter family member 1B3 appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Solute carrier organic anion transporter family member 1B3 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Solute carrier organic anion transporter family member 1B3 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Genes on human chromosome 12, Membrane protein stubs, Solute carrier family, so understanding it makes those chapters shorter.
In everyday life: Look for Solute carrier organic anion transporter family member 1B3 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Solute carrier organic anion transporter family member 1B3 in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Solute carrier organic anion transporter family member 1B3 means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Solute carrier organic anion transporter family member 1B3 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Solute carrier organic anion transporter family member 1B3 in simple terms?

Why does Solute carrier organic anion transporter family member 1B3 matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Solute carrier organic anion transporter family member 1B3?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Solute carrier organic anion transporter family member 1B3.