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Solypertine

Solypertine is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Solypertine rather than just read about it. In short: Solypertine (INNTooltip International Nonproprietary Name; developmental code name WIN-18413), also known as solypertine tartrate (USANTooltip United States Adopted Name) in the case of the tartrate salt, is a drug of the pertine group described as an antiadrenergic (or adrenolytic/sympatholytic) and as also potentially possessing neuroleptic properties which was never marketed. Structurally, it is a substituted try…

Solypertine — main illustration
Solypertine — illustration

Key takeaways

  • Solypertine belongs to chemistry; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Solypertine to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Solypertine from memory before moving on to harder problems.

Reference excerpt

Solypertine (INNTooltip International Nonproprietary Name; developmental code name WIN-18413), also known as solypertine tartrate (USANTooltip United States Adopted Name) in the case of the tartrate salt, is a drug of the pertine group described as an antiadrenergic (or adrenolytic/sympatholytic) and as also potentially possessing neuroleptic properties which was never marketed. Structurally, it is a substituted tryptamine and a piperazinylethylindole. The drug is closely structurally related to other "pertines" including alpertine, milipertine, and oxypertine, which are also tryptamines and piperazinylethylindoles. Solypertine can be synthesized from 5,6-methylenedioxyindole. The related drug oxypertine shows high affinity for the serotonin 5-HT2 and dopamine D2 receptors (Ki = 8.6 nM and 30 nM, respectively) and is also known to act as a catecholamine depleting agent. Oxypertine, milipertine, and solypertine all antagonize the behavioral effects of tryptamine, a serotonin receptor agonist, and apomorphine, a dopamine receptor agonist, in animals. ortho-Methoxyphenylpiperazine (oMeOPP) has been said to be a metabolite of milipertine and oxypertine. Solypertine was first described in the scientific literature by 1962.

See also Pertine NBOMe

References

Illustrations

Solypertine illustration

Worked examples

Example 1 — a first encounter with Solypertine

Start with the simplest possible case. Write down what Solypertine claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Solypertine before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Solypertine ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Solypertine

In research
Solypertine appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Solypertine in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Solypertine is common in secondary-school and first-year university syllabi. It links to neighbouring topics Abandoned drugs, Antihypertensive agents, Antipsychotics, so understanding it makes those chapters shorter.
In everyday life
Look for Solypertine outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Solypertine in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Solypertine means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Solypertine out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Solypertine in simple terms?

Solypertine (INNTooltip International Nonproprietary Name; developmental code name WIN-18413), also known as solypertine tartrate (USANTooltip United States Adopted Name) in the case of the tartrate salt, is a drug of the pertine group described as an antiadrenergic (or adrenolytic/sympatholytic) a…

Why does Solypertine matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Solypertine?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Solypertine.

Tags

  • Abandoned drugs
  • Antihypertensive agents
  • Antipsychotics
  • Drugs not assigned an ATC code
  • Methoxy compounds
  • Methylenedioxytryptamines
  • Pertines

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