astronomy

Stephanie Schorge

Stephanie Schorge is a astronomy topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Stephanie Schorge rather than just read about it. In short: Stephanie Schorge is a Professor of Neuroscience in the Department of Neuroscience, Physiology and Pharmacology at University College London. She is known for her research into mutations that cause neurological diseases.

Key takeaways

Stephanie Schorge belongs to astronomy; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Stephanie Schorge to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Stephanie Schorge from memory before moving on to harder problems.

Reference excerpt

Stephanie Schorge is a Professor of Neuroscience in the Department of Neuroscience, Physiology and Pharmacology at University College London. She is known for her research into mutations that cause neurological diseases.

Education and career Schorge received her B.S. from Yale University in 1994. She obtained a Ph.D. in Neuroscience from Brown University where she worked with Diane Lipscombe. Schorge has held postdoctoral positions at the Department of Pharmacology and the Institute of Neurology, both at the University College London. She has had a fellowship from the Worshipful Company of Pewterers and a university research fellowship from the Royal Society. In 2018 Schorge moved to the UCL School of Pharmacy to become professor in translational neuroscience and director of the research department of pharmacology. In 2021 she became head of the Department of Neuroscience, Physiology and Pharmacology (NPP). She was subsequently awarded the Sophia Jex-Blake Chair of Physiology.

Research Schorge is known for her research in how mutations in ion channels can cause neurological disease and how manipulating ion channels can be used to treat disease. She has worked on RNA processing in voltage gated calcium channels, single channel biophysics of NMDA receptors. and investigated the functional impacts of mutations in ion channels that are linked to human neurological disorders, the channelopathies. She has also examined the genetics and functions of mutations linked to epilepsy, particularly in sodium channels, and researched gene therapy treatments for epilepsy.

Selected publications Schorge, Stephanie; Colquhoun, David (2003-02-15). "Studies of NMDA Receptor Function and Stoichiometry with Truncated and Tandem Subunits". The Journal of Neuroscience. 23 (4): 1151–1158. doi:10.1523/JNEUROSCI.23-04-01151.2003. ISSN 0270-6474. PMC 6742241. PMID 12598603. Tate, Sarah K.; Depondt, Chantal; Sisodiya, Sanjay M.; Cavalleri, Gianpiero L.; Schorge, Stephanie; Soranzo, Nicole; Thom, Maria; Sen, Arjune; Shorvon, Simon D.; Sander, Josemir W.; Wood, Nicholas W.; Goldstein, David B. (2005-04-12). "Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin". Proceedings of the National Academy of Sciences. 102 (15): 5507–5512. Bibcode:2005PNAS..102.5507T. doi:10.1073/pnas.0407346102. ISSN 0027-8424. PMC 556232. PMID 15805193. Schorge, Stephanie; Leemput, Joyce van de; Singleton, Andrew; Houlden, Henry; Hardy, John (2010-05-01). "Human ataxias: a genetic dissection of inositol triphosphate receptor (ITPR1)-dependent signaling". Trends in Neurosciences. 33 (5): 211–219. doi:10.1016/j.tins.2010.02.005. ISSN 0166-2236. PMC 4684264. PMID 20226542. Wykes, Robert C.; Heeroma, Joost H.; Mantoan, Laura; Zheng, Kaiyu; MacDonald, Douglas C.; Deisseroth, Karl; Hashemi, Kevan S.; Walker, Matthew C.; Schorge, Stephanie; Kullmann, Dimitri M. (2012-11-21). "Optogenetic and Potassium Channel Gene Therapy in a Rodent Model of Focal Neocortical Epilepsy". Science Translational Medicine. 4 (161): 161ra152. doi:10.1126/scitranslmed.3004190. ISSN 1946-6234. PMC 3605784. PMID 23147003.

References

External links Stephanie Schorge publications indexed by Google Scholar

Worked examples

Example 1 — a first encounter with Stephanie Schorge

Start with the simplest possible case. Write down what Stephanie Schorge claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In astronomy, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Stephanie Schorge before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Stephanie Schorge ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Stephanie Schorge

In research: Stephanie Schorge appears in astronomy research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Stephanie Schorge in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Stephanie Schorge is common in secondary-school and first-year university syllabi. It links to neighbouring topics Academics of University College London, Brown University alumni, Living people, so understanding it makes those chapters shorter.
In everyday life: Look for Stephanie Schorge outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Stephanie Schorge in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Stephanie Schorge means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Stephanie Schorge out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Stephanie Schorge in simple terms?

Why does Stephanie Schorge matter?

Because it connects several astronomy ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Stephanie Schorge?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Stephanie Schorge.