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Wikipedia

Stollé synthesis

The Stollé synthesis is a series of chemical reactions that produce oxindoles from anilines and α-haloacid chlorides (or oxalyl chloride).

The first step is an amide coupling, while the second step is a Friedel–Crafts reaction. An improved procedure has been developed.

See also Indole Hinsberg oxindole synthesis

References

Tags

  • Carbon-carbon bond forming reactions
  • Heterocycle forming reactions
  • Name reactions