engineering

Succinyl-CoA:(R)-benzylsuccinate CoA-transferase

Succinyl-CoA:(R)-benzylsuccinate CoA-transferase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Succinyl-CoA:(R)-benzylsuccinate CoA-transferase rather than just read about it. In short: In enzymology, a succinyl-CoA:(R)-benzylsuccinate CoA-transferase (EC 2.8.3.15) is an enzyme that catalyzes the chemical reaction succinyl-CoA + (R)-2-benzylsuccinate ⇌ {\displaystyle \rightleftharpoons } succinate + (R)-2-benzylsuccinyl-CoA Thus, the two substrates of this enzyme are succinyl-CoA and (R)-2-benzylsuccinate, whereas its two products are succinate and (R)-2-benzylsuccinyl-CoA. This enzyme belongs to t…

Key takeaways

Succinyl-CoA:(R)-benzylsuccinate CoA-transferase belongs to engineering; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Succinyl-CoA:(R)-benzylsuccinate CoA-transferase to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Succinyl-CoA:(R)-benzylsuccinate CoA-transferase from memory before moving on to harder problems.

Reference excerpt

In enzymology, a succinyl-CoA:(R)-benzylsuccinate CoA-transferase (EC 2.8.3.15) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + (R)-2-benzylsuccinate ⇌ {\displaystyle \rightleftharpoons } succinate + (R)-2-benzylsuccinyl-CoA Thus, the two substrates of this enzyme are succinyl-CoA and (R)-2-benzylsuccinate, whereas its two products are succinate and (R)-2-benzylsuccinyl-CoA. This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase. This enzyme is also called benzylsuccinate CoA-transferase. This enzyme participates in benzoate degradation via coa ligation.

References

Leutwein C, Heider J (2001). "Succinyl-CoA:(R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria". J. Bacteriol. 183 (14): 4288–95. doi:10.1128/JB.183.14.4288-4295.2001. PMC 95319. PMID 11418570. Leutwein C, Heider J (1999). "Anaerobic toluene-catabolic pathway in denitrifying Thauera aromatica: activation and beta-oxidation of the first intermediate, (R)-(+)-benzylsuccinate". Microbiology. 145 (11): 3265–71. doi:10.1099/00221287-145-11-3265. PMID 10589736. Leuthner B, Heider J (2000). "Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate". J. Bacteriol. 182 (2): 272–7. doi:10.1128/JB.182.2.272-277.2000. PMC 94273. PMID 10629170. Heider J (2001). "A new family of CoA-transferases". FEBS Lett. 509 (3): 345–9. Bibcode:2001FEBSL.509..345H. doi:10.1016/S0014-5793(01)03178-7. PMID 11749953.

Worked examples

Example 1 — a first encounter with Succinyl-CoA:(R)-benzylsuccinate CoA-transferase

Start with the simplest possible case. Write down what Succinyl-CoA:(R)-benzylsuccinate CoA-transferase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Succinyl-CoA:(R)-benzylsuccinate CoA-transferase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Succinyl-CoA:(R)-benzylsuccinate CoA-transferase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Succinyl-CoA:(R)-benzylsuccinate CoA-transferase

In research: Succinyl-CoA:(R)-benzylsuccinate CoA-transferase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Succinyl-CoA:(R)-benzylsuccinate CoA-transferase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Succinyl-CoA:(R)-benzylsuccinate CoA-transferase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 2.8.3, Enzymes of unknown structure, Transferase stubs, so understanding it makes those chapters shorter.
In everyday life: Look for Succinyl-CoA:(R)-benzylsuccinate CoA-transferase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Succinyl-CoA:(R)-benzylsuccinate CoA-transferase in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Succinyl-CoA:(R)-benzylsuccinate CoA-transferase means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Succinyl-CoA:(R)-benzylsuccinate CoA-transferase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Succinyl-CoA:(R)-benzylsuccinate CoA-transferase in simple terms?

In enzymology, a succinyl-CoA:(R)-benzylsuccinate CoA-transferase (EC 2.8.3.15) is an enzyme that catalyzes the chemical reaction succinyl-CoA + (R)-2-benzylsuccinate ⇌ {\displaystyle \rightleftharpoons } succinate + (R)-2-benzylsuccinyl-CoA Thus, the two substrates of this enzyme are succinyl-CoA…

Why does Succinyl-CoA:(R)-benzylsuccinate CoA-transferase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Succinyl-CoA:(R)-benzylsuccinate CoA-transferase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Succinyl-CoA:(R)-benzylsuccinate CoA-transferase.