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Succinylglutamate desuccinylase

Succinylglutamate desuccinylase is a engineering topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Succinylglutamate desuccinylase rather than just read about it. In short: In enzymology, a succinylglutamate desuccinylase (EC 3.5.1.96) is an enzyme that catalyzes the chemical reaction N-succinyl-L-glutamate + H2O ⇌ {\displaystyle \rightleftharpoons } succinate + L-glutamate Thus, the two substrates of this enzyme are N-succinyl-L-glutamate and H2O, whereas its two products are succinate and L-glutamate. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bo…

Key takeaways

  • Succinylglutamate desuccinylase belongs to engineering; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Succinylglutamate desuccinylase to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Succinylglutamate desuccinylase from memory before moving on to harder problems.

Reference excerpt

In enzymology, a succinylglutamate desuccinylase (EC 3.5.1.96) is an enzyme that catalyzes the chemical reaction

N-succinyl-L-glutamate + H2O ⇌ {\displaystyle \rightleftharpoons } succinate + L-glutamate Thus, the two substrates of this enzyme are N-succinyl-L-glutamate and H2O, whereas its two products are succinate and L-glutamate. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-succinyl-L-glutamate amidohydrolase. Other names in common use include N2-succinylglutamate desuccinylase, SGDS, and AstE. This enzyme participates in arginine and proline metabolism.

References

Vander Wauven C, Stalon V (1985). "Occurrence of succinyl derivatives in the catabolism of arginine in Pseudomonas cepacia". J. Bacteriol. 164 (2): 882–6. doi:10.1128/jb.164.2.882-886.1985. PMC 214334. PMID 2865249. Cunin R, Glansdorff N, Pierard A, Stalon V (1986). "Biosynthesis and metabolism of arginine in bacteria". Microbiol. Rev. 50 (3): 314–52. doi:10.1128/mr.50.3.314-352.1986. PMC 373073. PMID 3534538. Cunin R, Glansdorff N, Pierard A, Stalon V (1987). "Erratum report: Biosynthesis and metabolism of arginine in bacteria". Microbiol. Rev. 51 (1): 178. doi:10.1128/mr.51.1.178-178b.1987. PMC 373097. PMID 16350242. Itoh Y (1997). "Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa". J. Bacteriol. 179 (23): 7280–90. doi:10.1128/jb.179.23.7280-7290.1997. PMC 179677. PMID 9393691. Schneider BL, Kiupakis AK, Reitzer LJ (1998). "Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli". J. Bacteriol. 180 (16): 4278–86. doi:10.1128/JB.180.16.4278-4286.1998. PMC 107427. PMID 9696779.

Worked examples

Example 1 — a first encounter with Succinylglutamate desuccinylase

Start with the simplest possible case. Write down what Succinylglutamate desuccinylase claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In engineering, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Succinylglutamate desuccinylase before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Succinylglutamate desuccinylase ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Succinylglutamate desuccinylase

In research
Succinylglutamate desuccinylase appears in engineering research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Succinylglutamate desuccinylase in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Succinylglutamate desuccinylase is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 3.5.1, EC 3.5 stubs, Enzymes of unknown structure, so understanding it makes those chapters shorter.
In everyday life
Look for Succinylglutamate desuccinylase outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Succinylglutamate desuccinylase in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Succinylglutamate desuccinylase means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Succinylglutamate desuccinylase out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Succinylglutamate desuccinylase in simple terms?

In enzymology, a succinylglutamate desuccinylase (EC 3.5.1.96) is an enzyme that catalyzes the chemical reaction N-succinyl-L-glutamate + H2O ⇌ {\displaystyle \rightleftharpoons } succinate + L-glutamate Thus, the two substrates of this enzyme are N-succinyl-L-glutamate and H2O, whereas its two pro…

Why does Succinylglutamate desuccinylase matter?

Because it connects several engineering ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Succinylglutamate desuccinylase?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Succinylglutamate desuccinylase.

Tags

  • EC 3.5.1
  • EC 3.5 stubs
  • Enzymes of unknown structure

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