ArticleslgStudy

chemistry

Sufotidine

Sufotidine is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Sufotidine rather than just read about it. In short: Sufotidine (INN, USAN, codenamed AH25352) is a long-acting competitive H2 receptor antagonist which was under development as an antiulcerant by Glaxo (now GlaxoSmithKline). It was planned to be a follow-up compound to ranitidine (Zantac).

Sufotidine — main illustration
Sufotidine — illustration

Key takeaways

  • Sufotidine belongs to chemistry; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Sufotidine to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Sufotidine from memory before moving on to harder problems.

Reference excerpt

Sufotidine (INN, USAN, codenamed AH25352) is a long-acting competitive H2 receptor antagonist which was under development as an antiulcerant by Glaxo (now GlaxoSmithKline). It was planned to be a follow-up compound to ranitidine (Zantac). When taken in doses of 600 mg twice daily it induced virtually 24-hour gastric anacidity thus closely resembling the antisecretory effect of the proton pump inhibitor omeprazole. Its development was terminated in 1989 from phase III clinical trials based on the appearance of carcinoid tumors in long-term toxicity testing in rodents.

Synthesis

See also Lavoltidine (previously known as loxtidine) — a similar compound in which methylsulfone group is replaced with hydroxyl

References

Illustrations

Sufotidine illustration

Worked examples

Example 1 — a first encounter with Sufotidine

Start with the simplest possible case. Write down what Sufotidine claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Sufotidine before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Sufotidine ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Sufotidine

In research
Sufotidine appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Sufotidine in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Sufotidine is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1-Piperidinyl compounds, Abandoned drugs, Drugs not assigned an ATC code, so understanding it makes those chapters shorter.
In everyday life
Look for Sufotidine outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
Ask Teacher Smith questions about this articleOpens your AI tutor with a question about “Sufotidine” →

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study Sufotidine in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Sufotidine means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Sufotidine out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Sufotidine in simple terms?

Sufotidine (INN, USAN, codenamed AH25352) is a long-acting competitive H2 receptor antagonist which was under development as an antiulcerant by Glaxo (now GlaxoSmithKline). It was planned to be a follow-up compound to ranitidine (Zantac).

Why does Sufotidine matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Sufotidine?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Sufotidine.

Tags

  • 1-Piperidinyl compounds
  • Abandoned drugs
  • Drugs not assigned an ATC code
  • H2 receptor antagonists
  • Mesyl compounds
  • Phenol ethers
  • Secondary amines
  • Triazoles

Keep exploring