Sulfinalol is a beta adrenergic receptor antagonist.
Synthesis
The preparation of sulfinalol begins by protection of the phenolic hydroxyl as its benzoate ester. Bromination followed by condensation with 4-(4-methoxyphenyl)butan-2-amine gives the amino ketone 3. Successive catalytic reduction and saponification affords amino alcohol 4. Oxidation of the sulfide to the sulfoxide with a reagent such as metaperiodate gives sulfinalol (5). The methyl group on a sulfoxide is sufficiently acidic to substitute for phenolic hydroxyl.
References

![Sulfinalol: Sulfinalol synthesis:[2][3]](https://upload.wikimedia.org/wikipedia/commons/thumb/3/36/Sulfinalol_synthesis.svg/500px-Sulfinalol_synthesis.svg.png?utm_source=en.wikipedia.org&utm_campaign=parser&utm_content=thumbnail)
