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chemistry

Surinabant

Surinabant is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Surinabant rather than just read about it. In short: Surinabant (SR147778) is a cannabinoid receptor type 1 antagonist developed by Sanofi-Aventis. It is being investigated as a potential treatment for nicotine addiction, to assist smoking cessation.

Surinabant — main illustration
Surinabant — illustration

Key takeaways

  • Surinabant belongs to chemistry; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Surinabant to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Surinabant from memory before moving on to harder problems.

Reference excerpt

Surinabant (SR147778) is a cannabinoid receptor type 1 antagonist developed by Sanofi-Aventis. It is being investigated as a potential treatment for nicotine addiction, to assist smoking cessation. It may also be developed as an anorectic drug to assist with weight loss, however there are already several CB1 antagonists or inverse agonists on the market or under development for this application, so surinabant is at present mainly being developed as an anti-smoking drug, with possible application in the treatment of other addictive disorders such as alcoholism. Other potential applications such as treatment of ADHD have also been proposed. A dose ranging study was done for smoking cessation in 2012; it did not improve success rate, but reduced weight gain. Inhibition of THC effects on heart rate was seen at 20 mg and 60 mg but not 5 mg.

See also Cannabinoid receptor antagonist List of investigational antipsychotics O-1269

References

Illustrations

Surinabant illustration
Surinabant illustration

Worked examples

Example 1 — a first encounter with Surinabant

Start with the simplest possible case. Write down what Surinabant claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Surinabant before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Surinabant ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Surinabant

In research
Surinabant appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Surinabant in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Surinabant is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1-Piperidinyl compounds, 4-Bromophenyl compounds, Abandoned drugs, so understanding it makes those chapters shorter.
In everyday life
Look for Surinabant outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Surinabant in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Surinabant means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Surinabant out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Surinabant in simple terms?

Surinabant (SR147778) is a cannabinoid receptor type 1 antagonist developed by Sanofi-Aventis. It is being investigated as a potential treatment for nicotine addiction, to assist smoking cessation.

Why does Surinabant matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Surinabant?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Surinabant.

Tags

  • 1-Piperidinyl compounds
  • 4-Bromophenyl compounds
  • Abandoned drugs
  • CB1 receptor antagonists
  • Cannabinoids
  • Dichlorophenyl compounds
  • Drugs not assigned an ATC code
  • Hallucinogen antidotes
  • Hydrazides
  • Pyrazolecarboxamides
  • Pyrazoles

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