Sym-norspermidine synthase (EC 2.5.1.23) is an enzyme characterised from Euglena gracilis that catalyzes a chemical reaction which transfers a propylamine three-carbon unit from S-adenosylmethioninamine to 1,3-diaminopropane, forming norspermidine, and giving 5′-methylthioadenosine as a byproduct: The enzyme found in Sulfolobus solfataricus can use other amines including putrescine as its substrate.
This enzyme is a transferase, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase. This enzyme participates in the urea cycle.
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