chemistry

Synapsinostat

Synapsinostat is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Synapsinostat rather than just read about it. In short: Synapsinostat, also known as CN13, is a histone deacetylase (HDAC) inhibitor and possible cognitive enhancer. It potently inhibits the class I HDAC1, HDAC2, and HDAC3, with IC50Tooltip half-maximal inhibitory concentration values of 39 nM, 41 nM, and 100 nM, respectively, whereas other HDACs were not assessed.

Key takeaways

Synapsinostat belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Synapsinostat to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Synapsinostat from memory before moving on to harder problems.

Reference excerpt

Synapsinostat, also known as CN13, is a histone deacetylase (HDAC) inhibitor and possible cognitive enhancer. It potently inhibits the class I HDAC1, HDAC2, and HDAC3, with IC50Tooltip half-maximal inhibitory concentration values of 39 nM, 41 nM, and 100 nM, respectively, whereas other HDACs were not assessed. The drug has been found to potently promote synaptogenesis in vitro. Synapsinostat was first described in the scientific literature by 2009. Subsequently, other improved analogues acting as HDAC inhibitors such as crebinostat and neurinostat, which show much greater potency, were described.

See also Histone deacetylase inhibitor Crebinostat Neurinostat Vorinostat

References

Worked examples

Example 1 — a first encounter with Synapsinostat

Start with the simplest possible case. Write down what Synapsinostat claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Synapsinostat before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Synapsinostat ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Synapsinostat

In research: Synapsinostat appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Synapsinostat in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Synapsinostat is common in secondary-school and first-year university syllabi. It links to neighbouring topics 2-Bromophenyl compounds, Alcohols, Amides, so understanding it makes those chapters shorter.
In everyday life: Look for Synapsinostat outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Synapsinostat in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Synapsinostat means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Synapsinostat out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Synapsinostat in simple terms?

Why does Synapsinostat matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Synapsinostat?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Synapsinostat.