science

TC OT 39

TC OT 39 is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand TC OT 39 rather than just read about it. In short: TC OT 39, also known as "compound 39", is a non-peptide partial agonist of the oxytocin and vasopressin V2 receptors (Ki = 147 nM and >1,000 nM, respectively) and antagonist of the vasopressin V1A receptor (Ki = 330 nM). The EC50Tooltip half-maximal effective concentration values of the drug were 33 nM at the oxytocin receptor and 850 nM at the vasopressin V2 receptor.

Key takeaways

TC OT 39 belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect TC OT 39 to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of TC OT 39 from memory before moving on to harder problems.

Reference excerpt

TC OT 39, also known as "compound 39", is a non-peptide partial agonist of the oxytocin and vasopressin V2 receptors (Ki = 147 nM and >1,000 nM, respectively) and antagonist of the vasopressin V1A receptor (Ki = 330 nM). The EC50Tooltip half-maximal effective concentration values of the drug were 33 nM at the oxytocin receptor and 850 nM at the vasopressin V2 receptor. TC OT 39 was first described in the scientific literature by Gary R. W. Pitt and colleagues in 2004. The drug was the first small-molecule oxytocin receptor agonist to be described, though it was the lead optimized compound of a described series of compounds. Subsequently, improved analogues like WAY-267,464 (2010), LIT-001 (2018), and LIT-002 (2026) were described.

See also Oxytocin receptor agonist WAY-267,464 LIT-001 LIT-002 KNX-100

References

Illustrations

Worked examples

Example 1 — a first encounter with TC OT 39

Start with the simplest possible case. Write down what TC OT 39 claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to TC OT 39 before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about TC OT 39 ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of TC OT 39

In research: TC OT 39 appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses TC OT 39 in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: TC OT 39 is common in secondary-school and first-year university syllabi. It links to neighbouring topics Benzamides, Benzodiazepines, Drugs not assigned an ATC code, so understanding it makes those chapters shorter.
In everyday life: Look for TC OT 39 outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

Affiliate

Preply — study more efficiently by working with a personal tutor. 50% off.

How to study TC OT 39 in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what TC OT 39 means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain TC OT 39 out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is TC OT 39 in simple terms?

Why does TC OT 39 matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study TC OT 39?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on TC OT 39.