biology

TRNADB

TRNADB is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand TRNADB rather than just read about it. In short: tRNAdb was a comprehensive biological database of transfer RNA (tRNA) sequences and tRNA genes. It originated as one of the first specialized compilations of nucleic acid sequences, starting as a print publication by Mathias Sprinzl in the late 1970s.

Key takeaways

TRNADB belongs to biology; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect TRNADB to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of TRNADB from memory before moving on to harder problems.

Reference excerpt

tRNAdb was a comprehensive biological database of transfer RNA (tRNA) sequences and tRNA genes. It originated as one of the first specialized compilations of nucleic acid sequences, starting as a print publication by Mathias Sprinzl in the late 1970s. It evolved into a web-based resource hosted at the University of Bayreuth and was later relaunched in 2009 as a more powerful relational database at the University of Leipzig. The database is now considered defunct, as the Leipzig-based resource is no longer active. Its role has largely been superseded by other modern tRNA databases.

Related databases

tRNADB-CE The tRNA Gene Database Curated by Experts (tRNADB-CE) is a database of tRNA genes developed and maintained by researchers at Niigata University and the Nagahama Institute of Bio-Science and Technology in Japan. A key feature of tRNADB-CE is its rigorous curation process. It uses three different tRNA gene prediction programs (tRNAscan-SE, ARAGORN, and tRNAfinder) and identifies any discordant results. These conflicting predictions are then manually reviewed by experts to ensure high accuracy.

GtRNAdb The Genomic tRNA Database (GtRNAdb) is a database of tRNA genes found in complete and draft genomes. Hosted at the University of California, Santa Cruz (UCSC) and maintained by the laboratory of Todd Lowe, GtRNAdb is built using predictions from a single, highly accurate software tool, tRNAscan-SE. It provides detailed information on genomic location, isotype, and secondary structure, and it is tightly integrated with the UCSC Genome Browser. Its focus is on providing high-quality, automated annotations of tRNA genes across all domains of life.

See also Transfer RNA (or tRNA) Transfer RNA-like structures

References

Worked examples

Example 1 — a first encounter with TRNADB

Start with the simplest possible case. Write down what TRNADB claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to TRNADB before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about TRNADB ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of TRNADB

In research: TRNADB appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses TRNADB in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: TRNADB is common in secondary-school and first-year university syllabi. It links to neighbouring topics Biological databases, Non-coding RNA, RNA, so understanding it makes those chapters shorter.
In everyday life: Look for TRNADB outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study TRNADB in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what TRNADB means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain TRNADB out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is TRNADB in simple terms?

Why does TRNADB matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study TRNADB?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on TRNADB.