tRNA (cytidine56-2'-O)-methyltransferase (EC 2.1.1.206, aTrm56, tRNA ribose 2'-O-methyltransferase aTrm56, PAB1040 (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytidine56-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction
S-adenosyl-L-methionine + cytidine56 in tRNA ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA The archaeal enzyme specifically catalyses the S-adenosyl-L-methionine dependent 2'-O-ribose methylation of cytidine at position 56 in tRNA transcripts.
References
External links TRNA+(cytidine56-2'-O)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
