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Tabernaemontanine

Tabernaemontanine is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Tabernaemontanine rather than just read about it. In short: Tabernaemontanine is a naturally occurring monoterpene indole alkaloid found in several species in the genus Tabernaemontana including Tabernaemontana divaricata. History Tabernaemontanine was first reported in 1939 but its structure was only fully confirmed in the 1970s as there was confusion in the original literature regarding the configuration of the ethyl group in the piperidine ring of this alkaloid and its is…

Tabernaemontanine — main illustration
Tabernaemontanine — illustration

Key takeaways

  • Tabernaemontanine belongs to science; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect Tabernaemontanine to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of Tabernaemontanine from memory before moving on to harder problems.

Reference excerpt

Tabernaemontanine is a naturally occurring monoterpene indole alkaloid found in several species in the genus Tabernaemontana including Tabernaemontana divaricata.

History Tabernaemontanine was first reported in 1939 but its structure was only fully confirmed in the 1970s as there was confusion in the original literature regarding the configuration of the ethyl group in the piperidine ring of this alkaloid and its isomer dregamine, so that their identities had been reversed. Both compounds were isolated from plants of the dogbane (Apocynaceae) family including Tabernaemontana coronaria. They have structures that are reduced versions of vobasine.

Biosynthesis

As with other Indole alkaloids, the biosynthesis of tabernaemontanine starts from the amino acid tryptophan. This is converted into strictosidine before further elaboration.

Natural occurrence

Tabernaemontanine is found commonly in the genera Tabernaemontana and Kopsia, including the species Ervatamia hirta, Tabernaemontana elegans and Tabernaemontana divaricata. The latter species is known to produce many other alkaloids including catharanthine, ibogamine and voacristine.

Research Plant metabolites have been of interest for their possible biological activity and alkaloids in particular are major subjects for ethnobotanical research. Tabernaemontanine has been studied, for example as a potential anti-cancer agent, for its antimalarial activity and in antifertility research. However, the alkaloid itself has not been developed as a drug.

See also Tabernanthine Ervaticine

References

Further reading Kitajima M, Takayama H (2016). Monoterpenoid Bisindole Alkaloids. The Alkaloids: Chemistry and Biology. Vol. 76. pp. 259–310. doi:10.1016/bs.alkal.2015.09.001. ISBN 978-0-12-804682-1. PMID 26827885. Namjoshi OA, Cook JM (2016). Sarpagine and Related Alkaloids. The Alkaloids: Chemistry and Biology. Vol. 76. pp. 63–169. doi:10.1016/bs.alkal.2015.08.002. ISBN 978-0-12-804682-1. PMC 4864735. PMID 26827883.

Illustrations

Tabernaemontanine illustration
Tabernaemontanine: Tabernaemontana divaricata, a source of tabernaemontanin
Tabernaemontana divaricata, a source of tabernaemontanin

Worked examples

Example 1 — a first encounter with Tabernaemontanine

Start with the simplest possible case. Write down what Tabernaemontanine claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Tabernaemontanine before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Tabernaemontanine ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Tabernaemontanine

In research
Tabernaemontanine appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses Tabernaemontanine in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
Tabernaemontanine is common in secondary-school and first-year university syllabi. It links to neighbouring topics Alkaloids found in Apocynaceae, Cyclic ketones, Indole alkaloids, so understanding it makes those chapters shorter.
In everyday life
Look for Tabernaemontanine outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study Tabernaemontanine in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what Tabernaemontanine means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain Tabernaemontanine out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Tabernaemontanine in simple terms?

Tabernaemontanine is a naturally occurring monoterpene indole alkaloid found in several species in the genus Tabernaemontana including Tabernaemontana divaricata. History Tabernaemontanine was first reported in 1939 but its structure was only fully confirmed in the 1970s as there was confusion in t…

Why does Tabernaemontanine matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Tabernaemontanine?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Tabernaemontanine.

Tags

  • Alkaloids found in Apocynaceae
  • Cyclic ketones
  • Indole alkaloids
  • Piperidines
  • Terpenes and terpenoids

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