science

Taliglucerase alfa

Taliglucerase alfa is a science topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Taliglucerase alfa rather than just read about it. In short: Taliglucerase alfa, sold under the brand name Elelyso among others, is a biopharmaceutical medication developed by Protalix and Pfizer. The drug, a recombinant glucocerebrosidase used to treat Gaucher's disease, is the first plant-made pharmaceutical to win approval by the U.S.

Key takeaways

Taliglucerase alfa belongs to science; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Taliglucerase alfa to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Taliglucerase alfa from memory before moving on to harder problems.

Reference excerpt

Taliglucerase alfa, sold under the brand name Elelyso among others, is a biopharmaceutical medication developed by Protalix and Pfizer. The drug, a recombinant glucocerebrosidase used to treat Gaucher's disease, is the first plant-made pharmaceutical to win approval by the U.S. Food and Drug Administration (FDA). Each vial has 200 units of taliglucerase alfa.

Approval history The US FDA New Drug Application (NDA) was granted approval in May 2012, for use in adults. The US FDA Supplemental New Drug Application (sNDA) for pediatric use was granted approved in August 2014. In Israel, the Israeli Ministry of Health granted approval in September 2012. In Brazil, the Brazilian Health Surveillance Agency (ANVISA) granted approval in March 2013. In Canada, Health Canada issued a Notice of Compliance in May 2014, for both adults and pediatric patients. Taliglucerase alfa is made by the Israeli biotherapeutics company Protalix and sold by the American pharmaceutical company Pfizer.

Society and culture

Economics For 2016, Elelyso was ranked third for pharmaceuticals with the highest cost-per-patient, with an average cost of $483,242 per year.

References

Worked examples

Example 1 — a first encounter with Taliglucerase alfa

Start with the simplest possible case. Write down what Taliglucerase alfa claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In science, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Taliglucerase alfa before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Taliglucerase alfa ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Taliglucerase alfa

In research: Taliglucerase alfa appears in science research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Taliglucerase alfa in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Taliglucerase alfa is common in secondary-school and first-year university syllabi. It links to neighbouring topics EC 3.2.1, Israeli inventions, so understanding it makes those chapters shorter.
In everyday life: Look for Taliglucerase alfa outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Taliglucerase alfa in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Taliglucerase alfa means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Taliglucerase alfa out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Taliglucerase alfa in simple terms?

Why does Taliglucerase alfa matter?

Because it connects several science ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Taliglucerase alfa?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Taliglucerase alfa.