biology

Tapas Kumar Kundu

Tapas Kumar Kundu is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Tapas Kumar Kundu rather than just read about it. In short: Tapas Kumar Kundu (born 2 January 1962) is an Indian molecular biologist, academician and at present the Director of Central Drug Research Institute, a prestigious research institute of Council of Scientific and Industrial Research at Lucknow. He is the head of the Transcription and Disease Laboratory of Jawaharlal Nehru Centre for Advanced Scientific Research.

Key takeaways

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Reference excerpt

Tapas Kumar Kundu (born 2 January 1962) is an Indian molecular biologist, academician and at present the Director of Central Drug Research Institute, a prestigious research institute of Council of Scientific and Industrial Research at Lucknow. He is the head of the Transcription and Disease Laboratory of Jawaharlal Nehru Centre for Advanced Scientific Research. He is known for his studies on the regulation of Gene expression and his contributions in cancer diagnostics and the development of new drug candidates for cancer and AIDS therapeutics. He is an elected fellow of the Indian Academy of Sciences, Indian National Science Academy and the National Academy of Sciences, India and a J. C. Bose National Fellow of the Department of Science and Technology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2005, for his contributions to biological sciences. He is also a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology.

Biography Born on 2 January 1962 at Hili, a border town near Balurghat in Dakshin Dinajpur district in the Indian state of West Bengal to Kalachand Kundu and Dipali couple, Tapas Kumar Kundu graduated in agriculture (BSc hons) from Bidhan Chandra Krishi Viswavidyalaya in 1986 and completed his master's degree in biochemistry from University of Agricultural Sciences, Bangalore in 1989, winning a gold medal for standing first in the master's degree examination. He enrolled for doctoral studies at the Indian Institute of Science in 1990 and secured a PhD under the guidance of M. R. S. Rao in 1995 for his thesis, Zinc-Metalloprotein Nature of Rat Spermatidal Protein TP2 and its Interactions with DNA. After a short stint at the National Institute of Genetics, Japan during 1995–96 as a visiting foreign research associate, he did his post-doctoral studies at the Laboratory of Biochemistry and Molecular Biology of Rockefeller University during 1996–99. Returning to India the same year, he joined Jawaharlal Nehru Centre for Advanced Scientific Research at their Molecular Biology and Genetics Unit where he became an assistant professor in 2005 and heads the Transcription and Disease Laboratory of the institution in the capacity of a JNCASR Silver Jubillee Professor since 2015. Kundu is a life member and a former vice president of the Society of Biological Chemists, India and is its incumbent president. He is a nominated member of American Chemical Society and American Society for Biochemistry and Molecular Biology and a member of the American Society for Microbiology. He was among the biologists who founded the Chemical Biology Society, India of the Indian Institute of Chemical Biology in 2013 and serves as it secretary. An adjunct professor at the Special Centre for Molecular Medicine of Jawaharlal Nehru University, he served as a member of the Reader Panel of Nature and is a former member of the editorial board of the Journal of Biological Chemistry (June 2011–September 2016). In 2019, the School of Biological Sciences, Madurai Kamaraj University had appointed him as a distinguished member of the national and international advisory committee to organize ICGB'19 (International Conference on Genome Biology 2019).

Legacy

Kundu's researches are principally focused on the regulation of transcription and P53 function using chromatin and associated proteins as well as on the functional genomics of transcriptional co-activators. His researches assisted in the identification of PC4 and its role as a functional component of chromatin and as an activator of P53. He demonstrated the histone chaperone activity and the acetylation of chromatin transcription and these findings have been reported to have helped in identifying new drug candidates. Extending his researches to cancer and AIDS therapeutics, he has identified small molecule modulators of chromatin modifying enzymes, a discovery which is reported to be helpful in developing new therapeutic protocols. Kundu has published one book, Epigenetics: Development and Disease, and a number of articles in peer-reviewed journals and Google Scholar, an online article repository, has listed 215 of them. Several of his research findings have been put to commercial use by various companies and he holds several patents for his works which include processes and compounds. He has delivered a number of featured lectures and is one of the organizers of the Asian Forum for the Chromatin and Chromosome Biology, a biennial event for the students and researchers of epigenetics and chromatin biology from Asian countries. He is also involved in popularizing science in the rural areas through science outreach programs and has delivered a series of lectures on Genes, Disease and Therapeutics, with student community as the audience.

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Worked examples

Example 1 — a first encounter with Tapas Kumar Kundu

Start with the simplest possible case. Write down what Tapas Kumar Kundu claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Tapas Kumar Kundu before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Tapas Kumar Kundu ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Tapas Kumar Kundu

In research: Tapas Kumar Kundu appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Tapas Kumar Kundu in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Tapas Kumar Kundu is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1962 births, 20th-century Indian biologists, 20th-century Indian inventors, so understanding it makes those chapters shorter.
In everyday life: Look for Tapas Kumar Kundu outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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Frequently asked questions

What is Tapas Kumar Kundu in simple terms?

Why does Tapas Kumar Kundu matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Tapas Kumar Kundu?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Tapas Kumar Kundu.