Taxusin is a taxane isolate derived from Taxus wallichiana. Taxusin can be used to synthesize taxadiene -diol and -triol derivatives via deoxygenation.
Taxol biosynthesis Taxusin is found in the yew tree Taxus cuspidata where it forms part of the pathway to taxol. The enzyme taxoid 7beta-hydroxylase, which uses oxygen and a reduced nicotinamide adenine dinucleotide (NADH) cofactor bound to a heme in cytochrome P450, converts it to a hydroxylated derivative:
See also Yunnanxane Hongdoushans
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