chemistry

Temafloxacin

Temafloxacin is a chemistry topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand Temafloxacin rather than just read about it. In short: Temafloxacin (marketed by Abbott Laboratories as Omniflox) is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths. It is not marketed in Europe.

Key takeaways

Temafloxacin belongs to chemistry; place it in that map before memorising details.
Learn the definition first, then one example that makes the definition concrete.
Connect Temafloxacin to a quantity you can measure, compute or draw — that is where exam questions come from.
Reproduce the core statement of Temafloxacin from memory before moving on to harder problems.

Reference excerpt

Temafloxacin (marketed by Abbott Laboratories as Omniflox) is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths. It is not marketed in Europe.

History Omniflox was approved to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections in the United States by the Food and Drug Administration in January 1992. Severe adverse reactions, including allergic reactions and hemolytic anemia, developed in over 100 patients during the first four months of its use, leading to three patient deaths. Abbott withdrew the drug from sale in June 1992.

Pharmacokinetics Following oral administration the compound is well absorbed from the gastrointestinal tract. The oral bioavailability is greater than 90%. Temafloxacin has a good tissue penetration in various biological fluids and tissues, particularly in the respiratory tissues, nasal secretions, tonsils, prostate and bone. In these districts the concentrations achieved are equal to or higher than those in serum. The fluoroquinolone has a 7-8 hour half-life. The penetration into the central nervous system (CNS)is less pronounced. The excretion from the body is primarily due to glomerular filtration in the kidneys.

Clinical uses The compound was indicated for treating lower respiratory tract infections (community-acquired pneumonia, exacerbations of chronic bronchitis), genital and urinary tract infections (prostatitis, gonococcal and non-gonococcal urethritis, cervicitis), skin and soft tissue infections.

Illustrations

Worked examples

Example 1 — a first encounter with Temafloxacin

Start with the simplest possible case. Write down what Temafloxacin claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In chemistry, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to Temafloxacin before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about Temafloxacin ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of Temafloxacin

In research: Temafloxacin appears in chemistry research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry: Engineering practice reuses Temafloxacin in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom: Temafloxacin is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1,4-di-hydro-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acids, Drugs developed by AbbVie, Fluoroquinolone antibiotics, so understanding it makes those chapters shorter.
In everyday life: Look for Temafloxacin outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.

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How to study Temafloxacin in 20 minutes

Read the reference excerpt below once, without taking notes.
Close the page and write down what Temafloxacin means in your own words.
Compare your version with the excerpt and mark what you missed.
Work through the three examples above with pen and paper.
Explain Temafloxacin out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is Temafloxacin in simple terms?

Why does Temafloxacin matter?

Because it connects several chemistry ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study Temafloxacin?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on Temafloxacin.