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The Online Journal of Current Clinical Trials

The Online Journal of Current Clinical Trials is a biology topic covered in the lgStudy science library. This page brings together a partial reference excerpt, illustrations, worked examples, real-world applications and a short study plan, so you can understand The Online Journal of Current Clinical Trials rather than just read about it. In short: The Online Journal of Current Clinical Trials was one of the first peer-reviewed online-only journals, publishing research articles, reviews, meta-analyses and letters relating to clinical trials from 1992 to 1996. It was founded by the American Association for the Advancement of Science (AAAS) and Online Computer Library Center (OCLC).

Key takeaways

  • The Online Journal of Current Clinical Trials belongs to biology; place it in that map before memorising details.
  • Learn the definition first, then one example that makes the definition concrete.
  • Connect The Online Journal of Current Clinical Trials to a quantity you can measure, compute or draw — that is where exam questions come from.
  • Reproduce the core statement of The Online Journal of Current Clinical Trials from memory before moving on to harder problems.

Reference excerpt

The Online Journal of Current Clinical Trials was one of the first peer-reviewed online-only journals, publishing research articles, reviews, meta-analyses and letters relating to clinical trials from 1992 to 1996. It was founded by the American Association for the Advancement of Science (AAAS) and Online Computer Library Center (OCLC). Access to the articles was lost when the journal closed in 1996 after being sold, but some access was restored in 2018.

History Plans by AAAS and OCLC for a digital journal began in 1989 and were announced in 1990. The journal launched on July 1, 1992, edited by Edward Huth, who was earlier the editor of Annals of Internal Medicine. As part of Primary Journals Online, AAAS was responsible for the editorial processes and OCLC for the technology side. Peer review was also done online. One aim of the journal was to reduce the time until publication of medical research. The launch was postponed from April due to technical difficulties, but it already had 1000 subscribers in the month of its launch and won the 1992 Database Product of the Year Award. The first issue published three clinical trials and several opinion pieces. Submissions were lower than anticipated; Cliff McKnight and colleagues noted that "Paradoxically, although the system was designed to be accessed directly by readers, it seems to have received a more enthusiastic reception from the information profession than from end users." AAAS sold the journal in 1994 to Chapman & Hall (later part of CRC Press and then Taylor & Francis), who hosted the journal at www.chapmanhall.com/cu.html. Library and information scientist Robin Peek noted in the mid-'90s that "Mounting a single journal is particularly problematic because most institutions are not willing to adapt their delivery infrastructure for one, or even a dozen, unique journal titles. Thus, even with the Internet, there remains the problem of achieving the needed mass." By 1996 OJCCT was the second-most cited electronic journal with 190 citations, and while its total citations in 1995 were "well below the median medical journal", "the average article in OJCCT [was] cited more than 88 percent of the e-journals indexed by JCR." As of 1996, OJCCT had published the then most-cited article in any electronic journal, a review of breast cancer screening.

Closure and preservation Despite the impact of the journal, it closed in 1996 and access was lost as no plans were made for preservation of the content. The former editors, including associate editor Kay Dickersin of Johns Hopkins School of Public Health, had considered putting copies of articles online but "we don't want to get into trouble". In March 2018, access was finally restored to over 50 of the around 80 articles by the digital preservation service Portico, with the permission of the copyright holder Taylor & Francis, after Dickersin worked with the JHU Sheridan Libraries, including librarian Mariyam Thohira, to organize an effort to find copies of the articles from colleagues and in libraries. The editor, Huth, provided many articles on a CD-ROM. Portico are seeking the missing content, which they hope may be in researchers' personal hardcopy archives.

Technical details The journal was accessible with an online subscription, initially costing US$110 per year via CompuServe and OCLC Net, using either GUI software called Guidon that used SGML and ran on DOS on an IBM-compatible computer or the Electronic Publishing Service, a more limited ASCII format also available on the internet. The system requirements were high for the time: an Intel 286 with 2 MB memory running Windows 3.0. By 1995, three more journals were available via Guidon on the Electronic Journals Online platform: The Online Journal of Knowledge Synthesis for Nursing, Electronics Letters Online, and APL Online. The journal was indexed on MEDLINE (and, from January 1994, Index Medicus), BIOSIS and WorldCat. Articles in OJCCT were published within 24 hours after the decision to accept. Access and support was limited to Monday-Friday 6am-10pm (Eastern Daylight Time), Saturday 8am-8pm, Sunday 12pm-8pm. Unlike other electronic journals at the time, the articles included figures and tables as well as typeset text. Downloading articles cost extra and printed copies could also be ordered from the publisher for a fee.

Legacy

OJCCT was the first online-only full text journal with graphics, and was followed by many other electronic journals, as they were called at the time, which changed how librarians provided content to their users and how publishers priced their content. By 1996, there were 115 electronic STM journals. The journal was the first electronic content to be indexed in Index Medicus. OJCCT introduced what is now called continuous publication, publishing articles as they are accepted rather than in an issue, with no space restrictions. In the first editorial, Huth promoted "the virtues of hypertext, the space electronic publishing offers for providing actual study data, and the ability to update meta-analyses". The journal was one of the first to have guidelines for the reporting of clinical trials and to encourage the publication of negative results.

References

Further reading Marrion, Dan (1992). "OCLC News". OCLC Micro. 8 (5). MCB UP: 5–8. doi:10.1108/eb055982.

External links Archive on Portico Entry at the US National Library of Medicine Early Clinical Trials E-Journal Makes a Comeback, Johns Hopkins Bloomberg School of Public Health The online journal of current clinical trials (1993 price list), OCLC OCLC Electronic Journals Online, listing from February 1997

Worked examples

Example 1 — a first encounter with The Online Journal of Current Clinical Trials

Start with the simplest possible case. Write down what The Online Journal of Current Clinical Trials claims or describes in one sentence, then invent the smallest concrete situation in which that sentence is true. In biology, the smallest case is usually a single object, a single equation or a single measurement. Check that every symbol or term in your sentence has a meaning in that case.

Example 2 — changing one variable

Take the situation from Example 1 and change exactly one quantity: double it, halve it, or set it to zero. Predict what should happen to The Online Journal of Current Clinical Trials before you calculate. Comparing your prediction with the result is the fastest way to find out whether you understand the idea or only the words.

Example 3 — an exam-style question

Typical questions about The Online Journal of Current Clinical Trials ask you to (a) state it precisely, (b) apply it to given data, and (c) explain a limitation. Practise writing all three answers in under five minutes; the third part is what separates a full-mark answer from an average one.

Applications of The Online Journal of Current Clinical Trials

In research
The Online Journal of Current Clinical Trials appears in biology research whenever the underlying quantities have to be modelled precisely. Papers usually cite it as a starting assumption and then explore where it breaks down.
In technology and industry
Engineering practice reuses The Online Journal of Current Clinical Trials in design rules, simulations and safety margins. Knowing the idea lets you read a specification sheet and understand why the numbers look the way they do.
In the classroom
The Online Journal of Current Clinical Trials is common in secondary-school and first-year university syllabi. It links to neighbouring topics 1992 establishments in the United States, 1996 disestablishments in the United States, Academic journals established in 1992, so understanding it makes those chapters shorter.
In everyday life
Look for The Online Journal of Current Clinical Trials outside the textbook — in sport, cooking, traffic, electronics or the sky above you. An example you found yourself is remembered far longer than one you were given.
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How to study The Online Journal of Current Clinical Trials in 20 minutes

  1. Read the reference excerpt below once, without taking notes.
  2. Close the page and write down what The Online Journal of Current Clinical Trials means in your own words.
  3. Compare your version with the excerpt and mark what you missed.
  4. Work through the three examples above with pen and paper.
  5. Explain The Online Journal of Current Clinical Trials out loud to somebody else — or to Teacher Smith in the lgStudy chat.

Frequently asked questions

What is The Online Journal of Current Clinical Trials in simple terms?

The Online Journal of Current Clinical Trials was one of the first peer-reviewed online-only journals, publishing research articles, reviews, meta-analyses and letters relating to clinical trials from 1992 to 1996. It was founded by the American Association for the Advancement of Science (AAAS) and…

Why does The Online Journal of Current Clinical Trials matter?

Because it connects several biology ideas at once: it gives you a definition you can apply, a quantity you can calculate, and a way to check whether a result is plausible.

How should I study The Online Journal of Current Clinical Trials?

Read the excerpt, restate it from memory, then work through the examples and applications listed on this page. The five-step study plan above takes about twenty minutes.

What does this page cover?

It gives you a compact reference excerpt plus original lgStudy explanations, examples, applications and study material on The Online Journal of Current Clinical Trials.

Tags

  • 1992 establishments in the United States
  • 1996 disestablishments in the United States
  • Academic journals established in 1992
  • Clinical trials
  • Continuous journals
  • General medical journals
  • Online-only journals
  • Publications disestablished in 1996
  • Taylor & Francis academic journals

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